Intravesicular Genomic DNA Enriched by Size Exclusion Chromatography Can Enhance Lung Cancer Oncogene Mutation Detection Sensitivity

Extracellular vesicles (EVs) are cell-derived structures surrounded by a lipid bilayer that carry RNA and DNA as potential templates for molecular diagnostics, e.g., in cancer genotyping. While it has been established that DNA templates appear on the outside of EVs, no consensus exists on which nucl...

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Detalles Bibliográficos
Autores principales: Van Hoof, Rebekka, Deville, Sarah, Hollanders, Karen, Berckmans, Pascale, Wagner, Patrick, Hooyberghs, Jef, Nelissen, Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785009/
https://www.ncbi.nlm.nih.gov/pubmed/36555692
http://dx.doi.org/10.3390/ijms232416052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785009/
https://www.ncbi.nlm.nih.gov/pubmed/36555692
http://dx.doi.org/10.3390/ijms232416052

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