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Mycobacterium tuberculosis PE_PGRS19 Induces Pyroptosis through a Non-Classical Caspase-11/GSDMD Pathway in Macrophages

The PE/PPE protein family commonly exists in pathogenic species, such as Mycobacterium tuberculosis, suggesting a role in virulence and its maintenance. However, the exact role of most PE/PPE proteins in host–pathogen interactions remains unknown. Here, we constructed a recombinant Mycobacterium sme...

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Detalles Bibliográficos
Autores principales:	Qian, Jianing, Hu, Youwei, Zhang, Xiao, Chi, Mingzhe, Xu, Siyue, Wang, Honghai, Zhang, Xuelian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785159/ https://www.ncbi.nlm.nih.gov/pubmed/36557726 http://dx.doi.org/10.3390/microorganisms10122473

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