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A Mathematical Model of Vaccinations Using New Fractional Order Derivative

Purpose: This paper studies a simple SVIR (susceptible, vaccinated, infected, recovered) type of model to investigate the coronavirus’s dynamics in Saudi Arabia with the recent cases of the coronavirus. Our purpose is to investigate coronavirus cases in Saudi Arabia and to predict the early eliminat...

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Autores principales: Asma, Yousaf, Mehreen, Afzaal, Muhammad, DarAssi, Mahmoud H., Khan, Muhammad Altaf, Alshahrani, Mohammad Y., Suliman, Muath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785217/
https://www.ncbi.nlm.nih.gov/pubmed/36560391
http://dx.doi.org/10.3390/vaccines10121980
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author Asma,
Yousaf, Mehreen
Afzaal, Muhammad
DarAssi, Mahmoud H.
Khan, Muhammad Altaf
Alshahrani, Mohammad Y.
Suliman, Muath
author_facet Asma,
Yousaf, Mehreen
Afzaal, Muhammad
DarAssi, Mahmoud H.
Khan, Muhammad Altaf
Alshahrani, Mohammad Y.
Suliman, Muath
author_sort Asma,
collection PubMed
description Purpose: This paper studies a simple SVIR (susceptible, vaccinated, infected, recovered) type of model to investigate the coronavirus’s dynamics in Saudi Arabia with the recent cases of the coronavirus. Our purpose is to investigate coronavirus cases in Saudi Arabia and to predict the early eliminations as well as future case predictions. The impact of vaccinations on COVID-19 is also analyzed. Methods: We consider the recently introduced fractional derivative known as the generalized Hattaf fractional derivative to extend our COVID-19 model. To obtain the fitted and estimated values of the parameters, we consider the nonlinear least square fitting method. We present the numerical scheme using the newly introduced fractional operator for the graphical solution of the generalized fractional differential equation in the sense of the Hattaf fractional derivative. Mathematical as well as numerical aspects of the model are investigated. Results: The local stability of the model at disease-free equilibrium is shown. Further, we consider real cases from Saudi Arabia since 1 May–4 August 2022, to parameterize the model and obtain the basic reproduction number [Formula: see text]. Further, we find the equilibrium point of the endemic state and observe the possibility of the backward bifurcation for the model and present their results. We present the global stability of the model at the endemic case, which we found to be globally asymptotically stable when [Formula: see text]. Conclusion: The simulation results using the recently introduced scheme are obtained and discussed in detail. We present graphical results with different fractional orders and found that when the order is decreased, the number of cases decreases. The sensitive parameters indicate that future infected cases decrease faster if face masks, social distancing, vaccination, etc., are effective.
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spelling pubmed-97852172022-12-24 A Mathematical Model of Vaccinations Using New Fractional Order Derivative Asma, Yousaf, Mehreen Afzaal, Muhammad DarAssi, Mahmoud H. Khan, Muhammad Altaf Alshahrani, Mohammad Y. Suliman, Muath Vaccines (Basel) Article Purpose: This paper studies a simple SVIR (susceptible, vaccinated, infected, recovered) type of model to investigate the coronavirus’s dynamics in Saudi Arabia with the recent cases of the coronavirus. Our purpose is to investigate coronavirus cases in Saudi Arabia and to predict the early eliminations as well as future case predictions. The impact of vaccinations on COVID-19 is also analyzed. Methods: We consider the recently introduced fractional derivative known as the generalized Hattaf fractional derivative to extend our COVID-19 model. To obtain the fitted and estimated values of the parameters, we consider the nonlinear least square fitting method. We present the numerical scheme using the newly introduced fractional operator for the graphical solution of the generalized fractional differential equation in the sense of the Hattaf fractional derivative. Mathematical as well as numerical aspects of the model are investigated. Results: The local stability of the model at disease-free equilibrium is shown. Further, we consider real cases from Saudi Arabia since 1 May–4 August 2022, to parameterize the model and obtain the basic reproduction number [Formula: see text]. Further, we find the equilibrium point of the endemic state and observe the possibility of the backward bifurcation for the model and present their results. We present the global stability of the model at the endemic case, which we found to be globally asymptotically stable when [Formula: see text]. Conclusion: The simulation results using the recently introduced scheme are obtained and discussed in detail. We present graphical results with different fractional orders and found that when the order is decreased, the number of cases decreases. The sensitive parameters indicate that future infected cases decrease faster if face masks, social distancing, vaccination, etc., are effective. MDPI 2022-11-22 /pmc/articles/PMC9785217/ /pubmed/36560391 http://dx.doi.org/10.3390/vaccines10121980 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Asma,
Yousaf, Mehreen
Afzaal, Muhammad
DarAssi, Mahmoud H.
Khan, Muhammad Altaf
Alshahrani, Mohammad Y.
Suliman, Muath
A Mathematical Model of Vaccinations Using New Fractional Order Derivative
title A Mathematical Model of Vaccinations Using New Fractional Order Derivative
title_full A Mathematical Model of Vaccinations Using New Fractional Order Derivative
title_fullStr A Mathematical Model of Vaccinations Using New Fractional Order Derivative
title_full_unstemmed A Mathematical Model of Vaccinations Using New Fractional Order Derivative
title_short A Mathematical Model of Vaccinations Using New Fractional Order Derivative
title_sort mathematical model of vaccinations using new fractional order derivative
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785217/
https://www.ncbi.nlm.nih.gov/pubmed/36560391
http://dx.doi.org/10.3390/vaccines10121980
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