The Effects of One-Point Mutation on the New Delhi Metallo Beta-Lactamase-1 Resistance toward Carbapenem Antibiotics and β-Lactamase Inhibitors: An In Silico Systematic Approach

Antibiotic resistance has been becoming more and more critical due to bacteria’s evolving hydrolysis enzymes. The NDM-1 enzyme could hydrolyze not only carbapenems but also most of β-lactam’s antibiotics and inhibitors. In fact, variant strains could impose a high impact on the resistance of bacteri...

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Detalles Bibliográficos
Autores principales: Tran, Van-Thanh, Tran, Viet-Hung, Nguyen, Dac-Nhan, Do, Tran-Giang-Son, Vo, Thanh-Phuong, Nguyen, Thi-Thao-Nhung, Huynh, Phuong Nguyen Hoai, Thai, Khac-Minh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785264/
https://www.ncbi.nlm.nih.gov/pubmed/36555726
http://dx.doi.org/10.3390/ijms232416083

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