Therapeutic Efficacy of Novel HDAC Inhibitors SPA3052 and SPA3074 against Intestinal Inflammation in a Murine Model of Colitis

Inflammatory bowel diseases (IBD) are digestive tract disorders that involve chronic inflammation with frequent recurrences. This study aimed to evaluate the efficacy of two novel histone deacetylase 8 (HDAC8) inhibitors, namely, SPA3052 and SPA3074, against dextran sulfate sodium (DSS)-induced expe...

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Detalles Bibliográficos
Autores principales: Yoon, Ji-In, Cho, Hyewon, Jeon, Raok, Sung, Mi-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785328/
https://www.ncbi.nlm.nih.gov/pubmed/36558966
http://dx.doi.org/10.3390/ph15121515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785328/
https://www.ncbi.nlm.nih.gov/pubmed/36558966
http://dx.doi.org/10.3390/ph15121515

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