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A Dietary Oxysterol, 7-Ketocholesterol, Exacerbates Imiquimod-Induced Psoriasis-like Dermatitis in Steatohepatitic Mice

Patients with psoriasis are at a higher risk of developing nonalcoholic fatty liver disease. We previously identified an oxidized derivative of cholesterol, 7-ketocholesterol (7KC), in diet-induced steatohepatitic mice. Here, we investigated whether 7KC exacerbates psoriasis-like dermatitis by accel...

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Detalles Bibliográficos
Autores principales: Saga, Ayami, Koseki, Masahiro, Kanno, Kotaro, Chang, Jiuyang, Higo, Tomoaki, Okuzaki, Daisuke, Okada, Takeshi, Inui, Hiroyasu, Asaji, Masumi, Tanaka, Katsunao, Omatsu, Takashi, Nishihara, Sae, Zhu, Yinghong, Ito, Kaori, Hattori, Hiroaki, Ichi, Ikuyo, Kamada, Yoshihiro, Ono, Masafumi, Saibara, Toshiji, Ohama, Tohru, Hikoso, Shungo, Nishida, Makoto, Yamashita, Shizuya, Sakata, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785382/
https://www.ncbi.nlm.nih.gov/pubmed/36555497
http://dx.doi.org/10.3390/ijms232415855