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scFASTCORMICS: A Contextualization Algorithm to Reconstruct Metabolic Multi-Cell Population Models from Single-Cell RNAseq Data

Tumours are composed of various cancer cell populations with different mutation profiles, phenotypes and metabolism that cause them to react to drugs in diverse manners. Increasing the resolution of metabolic models based on single-cell expression data will provide deeper insight into such metabolic...

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Detalles Bibliográficos
Autores principales: Pacheco, Maria Pires, Ji, Jimmy, Prohaska, Tessy, García, María Moscardó, Sauter, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785421/
https://www.ncbi.nlm.nih.gov/pubmed/36557249
http://dx.doi.org/10.3390/metabo12121211