Intranasal Administration of N-acetyl-L-cysteine Combined with Cell-Penetrating Peptide-Modified Polymer Nanomicelles as a Potential Therapeutic Approach for Amyotrophic Lateral Sclerosis

Intranasal administration is a promising route for direct drug delivery to the brain; its combination with nanocarriers enhances delivery. We have previously shown that intranasal administration combined with PEG-PCL-Tat (a nanocarrier) efficiently delivers drugs to the brain and exhibits excellent...

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Detalles Bibliográficos
Autores principales: Kurano, Takumi, Kanazawa, Takanori, Iioka, Shingo, Kondo, Hiromu, Kosuge, Yasuhiro, Suzuki, Toyofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785447/
https://www.ncbi.nlm.nih.gov/pubmed/36559085
http://dx.doi.org/10.3390/pharmaceutics14122590

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