Cargando…
Diode Laser and Polyimide Tape Enables Cheap and Fast Fabrication of Flexible Microfluidic Sensing Devices
Wearable devices are a new class of healthcare monitoring devices designed for use in close contact with the patient’s body. Such devices must be flexible to follow the contours of human anatomy. With numerous potential applications, a wide variety of flexible wearable devices have been created, tak...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785473/ https://www.ncbi.nlm.nih.gov/pubmed/36557513 http://dx.doi.org/10.3390/mi13122214 |
_version_ | 1784858057325412352 |
---|---|
author | Thaweeskulchai, Thana Schulte, Albert |
author_facet | Thaweeskulchai, Thana Schulte, Albert |
author_sort | Thaweeskulchai, Thana |
collection | PubMed |
description | Wearable devices are a new class of healthcare monitoring devices designed for use in close contact with the patient’s body. Such devices must be flexible to follow the contours of human anatomy. With numerous potential applications, a wide variety of flexible wearable devices have been created, taking various forms and functions. Therefore, different fabrication techniques and materials are employed, resulting in fragmentation of the list of equipment and materials needed to make different devices. This study attempted to simplify and streamline the fabrication process of all key components, including microfluidic chip and flexible electrode units. A combination of diode laser CNC machine and polyimide tape is used to fabricate flexible microfluidic chip and laser-induced graphene (LIG) electrodes, to create flexible microfluidic sensing devices. Laser ablation on polyimide tape can directly create microfluidic features on either PDMS substrates or LIG electrodes. The two components can be assembled to form a flexible microfluidic sensing device that can perform basic electrochemical analysis and conform to curved surfaces while undergoing microfluidic flow. This study has shown that simple, commonly available equipment and materials can be used to fabricate flexible microfluidic sensing devices quickly and easily, which is highly suitable for rapid prototyping of wearable devices. |
format | Online Article Text |
id | pubmed-9785473 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97854732022-12-24 Diode Laser and Polyimide Tape Enables Cheap and Fast Fabrication of Flexible Microfluidic Sensing Devices Thaweeskulchai, Thana Schulte, Albert Micromachines (Basel) Article Wearable devices are a new class of healthcare monitoring devices designed for use in close contact with the patient’s body. Such devices must be flexible to follow the contours of human anatomy. With numerous potential applications, a wide variety of flexible wearable devices have been created, taking various forms and functions. Therefore, different fabrication techniques and materials are employed, resulting in fragmentation of the list of equipment and materials needed to make different devices. This study attempted to simplify and streamline the fabrication process of all key components, including microfluidic chip and flexible electrode units. A combination of diode laser CNC machine and polyimide tape is used to fabricate flexible microfluidic chip and laser-induced graphene (LIG) electrodes, to create flexible microfluidic sensing devices. Laser ablation on polyimide tape can directly create microfluidic features on either PDMS substrates or LIG electrodes. The two components can be assembled to form a flexible microfluidic sensing device that can perform basic electrochemical analysis and conform to curved surfaces while undergoing microfluidic flow. This study has shown that simple, commonly available equipment and materials can be used to fabricate flexible microfluidic sensing devices quickly and easily, which is highly suitable for rapid prototyping of wearable devices. MDPI 2022-12-14 /pmc/articles/PMC9785473/ /pubmed/36557513 http://dx.doi.org/10.3390/mi13122214 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Thaweeskulchai, Thana Schulte, Albert Diode Laser and Polyimide Tape Enables Cheap and Fast Fabrication of Flexible Microfluidic Sensing Devices |
title | Diode Laser and Polyimide Tape Enables Cheap and Fast Fabrication of Flexible Microfluidic Sensing Devices |
title_full | Diode Laser and Polyimide Tape Enables Cheap and Fast Fabrication of Flexible Microfluidic Sensing Devices |
title_fullStr | Diode Laser and Polyimide Tape Enables Cheap and Fast Fabrication of Flexible Microfluidic Sensing Devices |
title_full_unstemmed | Diode Laser and Polyimide Tape Enables Cheap and Fast Fabrication of Flexible Microfluidic Sensing Devices |
title_short | Diode Laser and Polyimide Tape Enables Cheap and Fast Fabrication of Flexible Microfluidic Sensing Devices |
title_sort | diode laser and polyimide tape enables cheap and fast fabrication of flexible microfluidic sensing devices |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785473/ https://www.ncbi.nlm.nih.gov/pubmed/36557513 http://dx.doi.org/10.3390/mi13122214 |
work_keys_str_mv | AT thaweeskulchaithana diodelaserandpolyimidetapeenablescheapandfastfabricationofflexiblemicrofluidicsensingdevices AT schultealbert diodelaserandpolyimidetapeenablescheapandfastfabricationofflexiblemicrofluidicsensingdevices |