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Generation of Brain Microvascular Endothelial-like Cells from Human iPS Cell-Derived Endothelial Progenitor Cells Using TGF-β Receptor Inhibitor, Laminin 511 Fragment, and Neuronal Cell Culture Supplements

Brain microvascular endothelial cells (BMECs) constitute the blood–brain barrier (BBB), which prevents the transfer of substances into the brain. Recently, in vitro BBB models using human-induced pluripotent stem (iPS) cell-derived brain microvascular endothelial-like cells (iBMELCs) have been creat...

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Detalles Bibliográficos
Autores principales: Aoki, Hiromasa, Yamashita, Misaki, Hashita, Tadahiro, Iwao, Takahiro, Aoyama, Mineyoshi, Matsunaga, Tamihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785586/
https://www.ncbi.nlm.nih.gov/pubmed/36559191
http://dx.doi.org/10.3390/pharmaceutics14122697