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Generation of Brain Microvascular Endothelial-like Cells from Human iPS Cell-Derived Endothelial Progenitor Cells Using TGF-β Receptor Inhibitor, Laminin 511 Fragment, and Neuronal Cell Culture Supplements
Brain microvascular endothelial cells (BMECs) constitute the blood–brain barrier (BBB), which prevents the transfer of substances into the brain. Recently, in vitro BBB models using human-induced pluripotent stem (iPS) cell-derived brain microvascular endothelial-like cells (iBMELCs) have been creat...
Autores principales: | Aoki, Hiromasa, Yamashita, Misaki, Hashita, Tadahiro, Iwao, Takahiro, Aoyama, Mineyoshi, Matsunaga, Tamihide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785586/ https://www.ncbi.nlm.nih.gov/pubmed/36559191 http://dx.doi.org/10.3390/pharmaceutics14122697 |
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