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A Validated HPLC–Diode Array Detection Method for Therapeutic Drug Monitoring of Thiopurines in Pediatric Patients: From Bench to Bedside

Thiopurine drugs are part of the therapeutic armamentarium for pediatric patients suffering from inflammatory bowel disease (IBD) and acute lymphoblastic leukemia (ALL). The therapeutic drug monitoring of these drugs, consisting of measurements of the thiopurine metabolites thioguanine nucleotides (...

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Detalles Bibliográficos
Autores principales: Franzin, Martina, Curci, Debora, Lucafò, Marianna, Bramuzzo, Matteo, Rabusin, Marco, Fabretto, Antonella, Addobbati, Riccardo, Stocco, Gabriele, Decorti, Giuliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785603/
https://www.ncbi.nlm.nih.gov/pubmed/36557210
http://dx.doi.org/10.3390/metabo12121173