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The Circadian Syndrome Is a Significant and Stronger Predictor for Cardiovascular Disease than the Metabolic Syndrome—The NHANES Survey during 2005–2016

The study aimed to compare the predictive value of the Circadian Syndrome (CircS) and Metabolic Syndrome (MetS) for cardiovascular disease (CVD). We used data of 12,156 adults aged ≥20 years who attended National Health and Nutrition Examination Survey (NHANES) 2005–2016. Mortality was obtained from...

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Autores principales: Shi, Zumin, Tuomilehto, Jaakko, Kronfeld-Schor, Noga, Alberti, George, Stern, Naftali, El-Osta, Assam, Chai, Zhonglin, Bilu, Carmel, Einat, Haim, Zimmet, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785664/
https://www.ncbi.nlm.nih.gov/pubmed/36558476
http://dx.doi.org/10.3390/nu14245317
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author Shi, Zumin
Tuomilehto, Jaakko
Kronfeld-Schor, Noga
Alberti, George
Stern, Naftali
El-Osta, Assam
Chai, Zhonglin
Bilu, Carmel
Einat, Haim
Zimmet, Paul
author_facet Shi, Zumin
Tuomilehto, Jaakko
Kronfeld-Schor, Noga
Alberti, George
Stern, Naftali
El-Osta, Assam
Chai, Zhonglin
Bilu, Carmel
Einat, Haim
Zimmet, Paul
author_sort Shi, Zumin
collection PubMed
description The study aimed to compare the predictive value of the Circadian Syndrome (CircS) and Metabolic Syndrome (MetS) for cardiovascular disease (CVD). We used data of 12,156 adults aged ≥20 years who attended National Health and Nutrition Examination Survey (NHANES) 2005–2016. Mortality was obtained from the registry updated to 2019. The CircS was defined based on components of the MetS, in addition to short sleep and depression. Both the MetS and CircS were directly associated with self-reported history of CVD. The odds ratios for prevalent CVD associated with the CircS and MetS, respectively, were 2.92 (95% confidence interval (CI) 2.21–3.86) and 3.20 (2.38–4.30) in men, and 3.27 (2.34–4.59) and 3.04 (2.15–4.30) in women. The CircS had a better predictive power for prevalent CVD than that of MetS, as indicated by the higher positive predictive value (PPV); in men, the PPV for prevalent CVD with CircS was 23.1% and with MetS 20.9%, and in women these were 17.9% vs. 16.4%, respectively. However, the PPV of the CircS and MetS did not differ for the CVD mortality prediction. Women with CircS alone had a higher risk for both prevalent CVD and CVD mortality than those with MetS alone. In conclusion, the CircS is a significant and stronger predictor for CVD than the MetS in US adults.
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spelling pubmed-97856642022-12-24 The Circadian Syndrome Is a Significant and Stronger Predictor for Cardiovascular Disease than the Metabolic Syndrome—The NHANES Survey during 2005–2016 Shi, Zumin Tuomilehto, Jaakko Kronfeld-Schor, Noga Alberti, George Stern, Naftali El-Osta, Assam Chai, Zhonglin Bilu, Carmel Einat, Haim Zimmet, Paul Nutrients Article The study aimed to compare the predictive value of the Circadian Syndrome (CircS) and Metabolic Syndrome (MetS) for cardiovascular disease (CVD). We used data of 12,156 adults aged ≥20 years who attended National Health and Nutrition Examination Survey (NHANES) 2005–2016. Mortality was obtained from the registry updated to 2019. The CircS was defined based on components of the MetS, in addition to short sleep and depression. Both the MetS and CircS were directly associated with self-reported history of CVD. The odds ratios for prevalent CVD associated with the CircS and MetS, respectively, were 2.92 (95% confidence interval (CI) 2.21–3.86) and 3.20 (2.38–4.30) in men, and 3.27 (2.34–4.59) and 3.04 (2.15–4.30) in women. The CircS had a better predictive power for prevalent CVD than that of MetS, as indicated by the higher positive predictive value (PPV); in men, the PPV for prevalent CVD with CircS was 23.1% and with MetS 20.9%, and in women these were 17.9% vs. 16.4%, respectively. However, the PPV of the CircS and MetS did not differ for the CVD mortality prediction. Women with CircS alone had a higher risk for both prevalent CVD and CVD mortality than those with MetS alone. In conclusion, the CircS is a significant and stronger predictor for CVD than the MetS in US adults. MDPI 2022-12-14 /pmc/articles/PMC9785664/ /pubmed/36558476 http://dx.doi.org/10.3390/nu14245317 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Shi, Zumin
Tuomilehto, Jaakko
Kronfeld-Schor, Noga
Alberti, George
Stern, Naftali
El-Osta, Assam
Chai, Zhonglin
Bilu, Carmel
Einat, Haim
Zimmet, Paul
The Circadian Syndrome Is a Significant and Stronger Predictor for Cardiovascular Disease than the Metabolic Syndrome—The NHANES Survey during 2005–2016
title The Circadian Syndrome Is a Significant and Stronger Predictor for Cardiovascular Disease than the Metabolic Syndrome—The NHANES Survey during 2005–2016
title_full The Circadian Syndrome Is a Significant and Stronger Predictor for Cardiovascular Disease than the Metabolic Syndrome—The NHANES Survey during 2005–2016
title_fullStr The Circadian Syndrome Is a Significant and Stronger Predictor for Cardiovascular Disease than the Metabolic Syndrome—The NHANES Survey during 2005–2016
title_full_unstemmed The Circadian Syndrome Is a Significant and Stronger Predictor for Cardiovascular Disease than the Metabolic Syndrome—The NHANES Survey during 2005–2016
title_short The Circadian Syndrome Is a Significant and Stronger Predictor for Cardiovascular Disease than the Metabolic Syndrome—The NHANES Survey during 2005–2016
title_sort circadian syndrome is a significant and stronger predictor for cardiovascular disease than the metabolic syndrome—the nhanes survey during 2005–2016
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785664/
https://www.ncbi.nlm.nih.gov/pubmed/36558476
http://dx.doi.org/10.3390/nu14245317
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