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Is Evolutionary Conservation a Useful Predictor for Cancer Long Noncoding RNAs? Insights from the Cancer LncRNA Census 3
Evolutionary conservation is a measure of gene functionality that is widely used to prioritise long noncoding RNAs (lncRNA) in cancer research. Intriguingly, while updating our Cancer LncRNA Census (CLC), we observed an inverse relationship between year of discovery and evolutionary conservation. Th...
Autores principales: | Vancura, Adrienne, Gutierrez, Alejandro H., Hennig, Thorben, Pulido-Quetglas, Carlos, Slack, Frank J., Johnson, Rory, Haefliger, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785742/ https://www.ncbi.nlm.nih.gov/pubmed/36548181 http://dx.doi.org/10.3390/ncrna8060082 |
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