Amelioration of Hepatic Steatosis by the Androgen Receptor Inhibitor EPI-001 in Mice and Human Hepatic Cells Is Associated with the Inhibition of CYP2E1

Nonalcoholic fatty liver disease (NAFLD) is recognized as a metabolic disease characterized by hepatic steatosis. Despite the growing burden of NAFLD, approved pharmacological treatment is lacking. As an inhibitor of androgen receptor (AR), EPI-001 is being explored for the treatment of prostate can...

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Detalles Bibliográficos
Autores principales: Wang, Shuqin, Li, Xue, Xu, Weizhe, Gao, Jing, Wang, Yin, Jia, Xiaoyuan, Li, Gongchu, Pan, Qiuwei, Chen, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785868/
https://www.ncbi.nlm.nih.gov/pubmed/36555703
http://dx.doi.org/10.3390/ijms232416063

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