Cargando…

Design and Optimization of Lornoxicam Dispersible Tablets Using Quality by Design (QbD) Approach

The present study aims to design and optimize the lornoxicam dispersible tablet (LXDT) formulation using the Quality by design (QbD) approach. A randomized Box–Behnken experimental design was used to characterize the effect of the critical factors, such as filler (MCC/Mannitol) ratio, mixing time, a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Almotairi, Nawaf, Mahrous, Gamal M., Al-suwayeh, Saleh, Kazi, Mohsin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9785951/ https://www.ncbi.nlm.nih.gov/pubmed/36558914 http://dx.doi.org/10.3390/ph15121463

Ejemplares similares

Quality by Design (QbD)-Based Numerical and Graphical Optimization Technique for the Development of Osmotic Pump Controlled-Release Metoclopramide HCl Tablets
por: Farooqi, Sadaf, et al.
Publicado: (2020)

Design and dermatokinetic appraisal of lornoxicam-loaded ultrafine self-nanoemulsion hydrogel for the management of inflammation: In vitro and in vivo studies
por: Al-Suwayeh, Saleh A., et al.
Publicado: (2023)

Pharmaceutical Development and Design of Thermosensitive Liposomes Based on the QbD Approach
por: Dobó, Dorina Gabriella, et al.
Publicado: (2022)

Industrial application of QbD and NIR chemometric models in quality improvement of immediate release tablets
por: Ramadan, Ahmed, et al.
Publicado: (2021)

A QbD Approach to Design and to Optimize the Self-Emulsifying Resveratrol–Phospholipid Complex to Enhance Drug Bioavailability through Lymphatic Transport
por: Gausuzzaman, Syed Abul Layes, et al.
Publicado: (2022)

The way to a design space for an animal cell culture process according to Quality by Design (QbD)
por: Puskeiler, Robert, et al.
Publicado: (2011)

Novel NIR modeling design and assignment in process quality control of Honeysuckle flower by QbD
por: Ma, Lijuan, et al.
Publicado: (2020)

Quality by Design (QbD) Approach for a Nanoparticulate Imiquimod Formulation as an Investigational Medicinal Product
por: Pielenhofer, Jonas, et al.
Publicado: (2023)

Application of the Quality by Design Concept (QbD) in the Development of Hydrogel-Based Drug Delivery Systems
por: Mohseni-Motlagh, S. Farid, et al.
Publicado: (2023)

An Updated Risk Assessment as Part of the QbD-Based Liposome Design and Development
por: Németh, Zsófia, et al.
Publicado: (2021)

Optimization of the Micellar-Based In Situ Gelling Systems Posaconazole with Quality by Design (QbD) Approach and Characterization by In Vitro Studies
por: Durgun, Meltem Ezgi, et al.
Publicado: (2022)

QbD Consideration for Developing a Double-Layered Tablet into a Single-Layered Tablet with Telmisartan and Amlodipine
por: Kim, Joo-Eun, et al.
Publicado: (2022)

Quality by Design (QbD) Based Method for Estimation of Xanthohumol in Bulk and Solid Lipid Nanoparticles and Validation
por: Harish, Vancha, et al.
Publicado: (2023)

Quality by Design (QbD) and Design of Experiments (DOE) as a Strategy for Tuning Lipid Nanoparticle Formulations for RNA Delivery
por: Gurba-Bryśkiewicz, Lidia, et al.
Publicado: (2023)

Toward QbD Process Understanding on DNA Vaccine Purification Using Design of Experiment
por: Hocharoen, Lalintip, et al.
Publicado: (2021)

Process optimization for the synthesis of functionalized Au@AgNPs for specific detection of Hg(2+) based on quality by design (QbD)
por: Zhang, Hui, et al.
Publicado: (2022)

Quality by design (QbD) approach in processing polymeric nanoparticles loading anticancer drugs by high pressure homogenizer
por: Soni, Govind, et al.
Publicado: (2020)

Design Space and QbD Approach for Production of Drug Nanocrystals by Wet Media Milling Techniques
por: Peltonen, Leena
Publicado: (2018)

Compression-coated pulsatile chronomodulated therapeutic system: QbD assisted optimization
por: Aldawsari, Hibah M., et al.
Publicado: (2022)

Evaluations of Quality by Design (QbD) Elements Impact for Developing Niosomes as a Promising Topical Drug Delivery Platform
por: Shah, Parinbhai, et al.
Publicado: (2020)

QbD based development of HPLC method for simultaneous quantification of Telmisartan and Hydrochlorothiazide impurities in tablets dosage form
por: Palakurthi, Ashok K., et al.
Publicado: (2020)

A Cost Effective (QbD) Approach in the Development and Optimization of Rosiglitazone Maleate Mucoadhesive Extended Release Tablets –In Vitro and Ex Vivo
por: Chappidi, Suryaprakash Reddy, et al.
Publicado: (2019)

Evaluation of Skin Permeation and Analgesic Activity Effects of Carbopol Lornoxicam Topical Gels Containing Penetration Enhancer
por: Al-Suwayeh, Saleh A., et al.
Publicado: (2014)

Lornoxicam gastro retentive floating matrix tablets: Design and in vitro evaluation
por: Sathiyaraj, S., et al.
Publicado: (2011)

Implementation of Quality by Design (QbD) Principles in Regulatory Dossiers of Medicinal Products in the European Union (EU) Between 2014 and 2019
por: ter Horst, Judith P., et al.
Publicado: (2021)

Implementation of QbD Approach to the Analytical Method Development and Validation for the Estimation of Metformin Hydrochloride in Tablet Dosage Forms by HPLC
por: Sha’at, Mousa, et al.
Publicado: (2022)

Dasatinib-Loaded Topical Nano-Emulgel for Rheumatoid Arthritis: Formulation Design and Optimization by QbD, In Vitro, Ex Vivo, and In Vivo Evaluation
por: Donthi, Mahipal Reddy, et al.
Publicado: (2023)

Early Implementation of QbD in Biopharmaceutical Development: A Practical Example
por: Zurdo, Jesús, et al.
Publicado: (2015)

Quality by Design (QbD) based process optimisation to develop functionalised particles with modified release properties using novel dry particle coating technique
por: Dahmash, Eman Z., et al.
Publicado: (2018)

QbD Based Media Development for the Production of Fab Fragments in E. coli
por: Kumar, Deepak, et al.
Publicado: (2019)

QbD Enabled Azacitidine Loaded Liposomal Nanoformulation and Its In Vitro Evaluation
por: Kesharwani, Prashant, et al.
Publicado: (2021)

Double Optimization of Rivastigmine-Loaded Nanostructured Lipid Carriers (NLC) for Nose-to-Brain Delivery Using the Quality by Design (QbD) Approach: Formulation Variables and Instrumental Parameters
por: Cunha, Sara, et al.
Publicado: (2020)

Development of a Resveratrol Nanosuspension Using the Antisolvent Precipitation Method without Solvent Removal, Based on a Quality by Design (QbD) Approach
por: Kuk, Do-Hoon, et al.
Publicado: (2019)

QbD Design, Formulation, Optimization and Evaluation of Trans-Tympanic Reverse Gelatination Gel of Norfloxacin: Investigating Gene-Gene Interactions to Enhance Therapeutic Efficacy
por: Budhori, Amit, et al.
Publicado: (2023)

Design and Evaluation of S-Protected Thiolated-Based Itopride Hydrochloride Polymeric Nanocrystals for Functional Dyspepsia: QbD-Driven Optimization, In Situ, In Vitro, and In Vivo Investigation
por: Badr, Moutaz Y., et al.
Publicado: (2023)

QbD based approach for optimization of Tenofovir disoproxil fumarate loaded liquid crystal precursor with improved permeability
por: Patil, Sharvil, et al.
Publicado: (2017)

The Use of the QbD Approach to Optimize the Co-Loading of Simvastatin and Doxorubicin in Liposomes for a Synergistic Anticancer Effect
por: Barbalata, Cristina-Ioana, et al.
Publicado: (2022)

Development of Bedaquiline-Loaded SNEDDS Using Quality by Design (QbD) Approach to Improve Biopharmaceutical Attributes for the Management of Multidrug-Resistant Tuberculosis (MDR-TB)
por: Jahan, Rao Nargis, et al.
Publicado: (2023)

Implementation of QbD strategies in the inoculum expansion of a mAb production process
por: Böhl, Ole Jacob, et al.
Publicado: (2020)

Fixed Dose Single Tablet Formulation with Differential Release of Amlodipine Besylate and Simvastatin and Its Pharmacokinetic Profile: QbD and Risk Assessment Approach
por: Kanwal, Ummarah, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_542vs5f9b1s8nhic3ggl80k3n3