The Application and Challenge of Binder Jet 3D Printing Technology in Pharmaceutical Manufacturing

Three-dimensional (3D) printing is an additive manufacturing technique that creates objects under computer control. Owing to the rapid advancement of science and technology, 3D printing technology has been widely utilized in processing and manufacturing but rarely used in the pharmaceutical field. T...

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Autores principales: Chen, Xuejun, Wang, Shanshan, Wu, Jie, Duan, Shuwei, Wang, Xiaolong, Hong, Xiaoxuan, Han, Xiaolu, Li, Conghui, Kang, Dongzhou, Wang, Zengming, Zheng, Aiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786002/
https://www.ncbi.nlm.nih.gov/pubmed/36559082
http://dx.doi.org/10.3390/pharmaceutics14122589
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author Chen, Xuejun
Wang, Shanshan
Wu, Jie
Duan, Shuwei
Wang, Xiaolong
Hong, Xiaoxuan
Han, Xiaolu
Li, Conghui
Kang, Dongzhou
Wang, Zengming
Zheng, Aiping
author_facet Chen, Xuejun
Wang, Shanshan
Wu, Jie
Duan, Shuwei
Wang, Xiaolong
Hong, Xiaoxuan
Han, Xiaolu
Li, Conghui
Kang, Dongzhou
Wang, Zengming
Zheng, Aiping
author_sort Chen, Xuejun
collection PubMed
description Three-dimensional (3D) printing is an additive manufacturing technique that creates objects under computer control. Owing to the rapid advancement of science and technology, 3D printing technology has been widely utilized in processing and manufacturing but rarely used in the pharmaceutical field. The first commercial form of Spritam(®) immediate-release tablet was approved by FDA in 2015, which promoted the advancement of 3D printing technology in pharmaceutical development. Three-dimensional printing technology is able to meet individual treatment demands with customized size, shape, and release rate, which overcomes the difficulties of traditional pharmaceutical technology. This paper intends to discuss the critical process parameters of binder jet 3D printing technology, list its application in pharmaceutical manufacturing in recent years, summarize the still-open questions, and demonstrate its great potential in the pharmaceutical industry.
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spelling pubmed-97860022022-12-24 The Application and Challenge of Binder Jet 3D Printing Technology in Pharmaceutical Manufacturing Chen, Xuejun Wang, Shanshan Wu, Jie Duan, Shuwei Wang, Xiaolong Hong, Xiaoxuan Han, Xiaolu Li, Conghui Kang, Dongzhou Wang, Zengming Zheng, Aiping Pharmaceutics Review Three-dimensional (3D) printing is an additive manufacturing technique that creates objects under computer control. Owing to the rapid advancement of science and technology, 3D printing technology has been widely utilized in processing and manufacturing but rarely used in the pharmaceutical field. The first commercial form of Spritam(®) immediate-release tablet was approved by FDA in 2015, which promoted the advancement of 3D printing technology in pharmaceutical development. Three-dimensional printing technology is able to meet individual treatment demands with customized size, shape, and release rate, which overcomes the difficulties of traditional pharmaceutical technology. This paper intends to discuss the critical process parameters of binder jet 3D printing technology, list its application in pharmaceutical manufacturing in recent years, summarize the still-open questions, and demonstrate its great potential in the pharmaceutical industry. MDPI 2022-11-24 /pmc/articles/PMC9786002/ /pubmed/36559082 http://dx.doi.org/10.3390/pharmaceutics14122589 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chen, Xuejun
Wang, Shanshan
Wu, Jie
Duan, Shuwei
Wang, Xiaolong
Hong, Xiaoxuan
Han, Xiaolu
Li, Conghui
Kang, Dongzhou
Wang, Zengming
Zheng, Aiping
The Application and Challenge of Binder Jet 3D Printing Technology in Pharmaceutical Manufacturing
title The Application and Challenge of Binder Jet 3D Printing Technology in Pharmaceutical Manufacturing
title_full The Application and Challenge of Binder Jet 3D Printing Technology in Pharmaceutical Manufacturing
title_fullStr The Application and Challenge of Binder Jet 3D Printing Technology in Pharmaceutical Manufacturing
title_full_unstemmed The Application and Challenge of Binder Jet 3D Printing Technology in Pharmaceutical Manufacturing
title_short The Application and Challenge of Binder Jet 3D Printing Technology in Pharmaceutical Manufacturing
title_sort application and challenge of binder jet 3d printing technology in pharmaceutical manufacturing
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786002/
https://www.ncbi.nlm.nih.gov/pubmed/36559082
http://dx.doi.org/10.3390/pharmaceutics14122589
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