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Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics
The development of non-invasive optoelectronic technologies for human blood monitoring is one of the important research areas for medicine. A critical analysis of optoelectronic methods of blood research and the micromechanical systems based on them is carried out in this article. A design realizati...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786004/ https://www.ncbi.nlm.nih.gov/pubmed/36557540 http://dx.doi.org/10.3390/mi13122241 |
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author | Khlynov, Ruslan D. Ryzhova, Victoria A. Yarishev, Sergey N. Konyakhin, Igor A. Korotaev, Valery V. Shelepin, Yuri E. Djamiykov, Todor S. Marinov, Marin B. |
author_facet | Khlynov, Ruslan D. Ryzhova, Victoria A. Yarishev, Sergey N. Konyakhin, Igor A. Korotaev, Valery V. Shelepin, Yuri E. Djamiykov, Todor S. Marinov, Marin B. |
author_sort | Khlynov, Ruslan D. |
collection | PubMed |
description | The development of non-invasive optoelectronic technologies for human blood monitoring is one of the important research areas for medicine. A critical analysis of optoelectronic methods of blood research and the micromechanical systems based on them is carried out in this article. A design realization of a polarizing portable system for non-invasive monitoring of hematocrit as one of the basic homeostatic constants of the human body containing information about the microphysical parameters of blood cells has been substantiated. A physical model of polarized radiation conversion in a video information system of laser sensing of a biological research object has been formed. Visual and quantitative differences in the spatial distribution of polarization parameters of the scattered radiation for the states of the body with different hematocrit levels have been revealed. A scheme of a multichannel imaging portable system, based on a smartphone using miniature optical and microelectronic components of information conversion for non-invasive monitoring of microphysical blood parameters, has been created. The system implements the principle of polarimetric blood photometry and a multiparametric analysis of the polarization properties of the laser radiation scattered by blood. The developed portable optoelectronic system, based on a smartphone, can be used for rapid blood diagnostics in disaster medicine and the presence of clinical contraindications to the formation of invasive tests. The proposed polarization-based approach is a promising automated alternative to traditional devices and systems for the research of microphysical blood parameters. |
format | Online Article Text |
id | pubmed-9786004 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97860042022-12-24 Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics Khlynov, Ruslan D. Ryzhova, Victoria A. Yarishev, Sergey N. Konyakhin, Igor A. Korotaev, Valery V. Shelepin, Yuri E. Djamiykov, Todor S. Marinov, Marin B. Micromachines (Basel) Article The development of non-invasive optoelectronic technologies for human blood monitoring is one of the important research areas for medicine. A critical analysis of optoelectronic methods of blood research and the micromechanical systems based on them is carried out in this article. A design realization of a polarizing portable system for non-invasive monitoring of hematocrit as one of the basic homeostatic constants of the human body containing information about the microphysical parameters of blood cells has been substantiated. A physical model of polarized radiation conversion in a video information system of laser sensing of a biological research object has been formed. Visual and quantitative differences in the spatial distribution of polarization parameters of the scattered radiation for the states of the body with different hematocrit levels have been revealed. A scheme of a multichannel imaging portable system, based on a smartphone using miniature optical and microelectronic components of information conversion for non-invasive monitoring of microphysical blood parameters, has been created. The system implements the principle of polarimetric blood photometry and a multiparametric analysis of the polarization properties of the laser radiation scattered by blood. The developed portable optoelectronic system, based on a smartphone, can be used for rapid blood diagnostics in disaster medicine and the presence of clinical contraindications to the formation of invasive tests. The proposed polarization-based approach is a promising automated alternative to traditional devices and systems for the research of microphysical blood parameters. MDPI 2022-12-16 /pmc/articles/PMC9786004/ /pubmed/36557540 http://dx.doi.org/10.3390/mi13122241 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Khlynov, Ruslan D. Ryzhova, Victoria A. Yarishev, Sergey N. Konyakhin, Igor A. Korotaev, Valery V. Shelepin, Yuri E. Djamiykov, Todor S. Marinov, Marin B. Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics |
title | Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics |
title_full | Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics |
title_fullStr | Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics |
title_full_unstemmed | Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics |
title_short | Analysis of Polarization Images in the Microphysical Blood Parameters Research for the Hematocrit Diagnostics |
title_sort | analysis of polarization images in the microphysical blood parameters research for the hematocrit diagnostics |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786004/ https://www.ncbi.nlm.nih.gov/pubmed/36557540 http://dx.doi.org/10.3390/mi13122241 |
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