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HIV/AIDS Mathematical Model of Triangle Transmission

In this paper, a mathematical analysis of the HIV/AIDS deterministic model studied in the paper called Mathematical Model of HIV/AIDS Considering Sexual Preferences Under Antiretroviral Therapy, a case study in the previous works preformed by Espitia is performed. The objective is to gain insight in...

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Autores principales: Espitia Morillo, Cristian Camilo, Meyer, João Frederico da Costa Azevedo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786322/
https://www.ncbi.nlm.nih.gov/pubmed/36560753
http://dx.doi.org/10.3390/v14122749
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author Espitia Morillo, Cristian Camilo
Meyer, João Frederico da Costa Azevedo
author_facet Espitia Morillo, Cristian Camilo
Meyer, João Frederico da Costa Azevedo
author_sort Espitia Morillo, Cristian Camilo
collection PubMed
description In this paper, a mathematical analysis of the HIV/AIDS deterministic model studied in the paper called Mathematical Model of HIV/AIDS Considering Sexual Preferences Under Antiretroviral Therapy, a case study in the previous works preformed by Espitia is performed. The objective is to gain insight into the qualitative dynamics of the model determining the conditions for the persistence or effective control of the disease in the community through the study of basic properties such as positiveness and boundedness; the calculus of the basic reproduction number; stationary points such as disease-free equilibrium (DFE), boundary equilibrium (BE) and endemic equilibrium (EE); and the local stability (LAS) of disease-free equilibrium. The findings allow us to conclude that the best way to reduce contagion and consequently reach a DFE is thought to be the reduction in the rate of homosexual partners, as they are the most affected population by the virus and are therefore the most likely to become infected and spread it. Increasing the departure rate of infected individuals leads to a decrease in untreated infected heterosexual men and untreated infected women.
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spelling pubmed-97863222022-12-24 HIV/AIDS Mathematical Model of Triangle Transmission Espitia Morillo, Cristian Camilo Meyer, João Frederico da Costa Azevedo Viruses Article In this paper, a mathematical analysis of the HIV/AIDS deterministic model studied in the paper called Mathematical Model of HIV/AIDS Considering Sexual Preferences Under Antiretroviral Therapy, a case study in the previous works preformed by Espitia is performed. The objective is to gain insight into the qualitative dynamics of the model determining the conditions for the persistence or effective control of the disease in the community through the study of basic properties such as positiveness and boundedness; the calculus of the basic reproduction number; stationary points such as disease-free equilibrium (DFE), boundary equilibrium (BE) and endemic equilibrium (EE); and the local stability (LAS) of disease-free equilibrium. The findings allow us to conclude that the best way to reduce contagion and consequently reach a DFE is thought to be the reduction in the rate of homosexual partners, as they are the most affected population by the virus and are therefore the most likely to become infected and spread it. Increasing the departure rate of infected individuals leads to a decrease in untreated infected heterosexual men and untreated infected women. MDPI 2022-12-09 /pmc/articles/PMC9786322/ /pubmed/36560753 http://dx.doi.org/10.3390/v14122749 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Espitia Morillo, Cristian Camilo
Meyer, João Frederico da Costa Azevedo
HIV/AIDS Mathematical Model of Triangle Transmission
title HIV/AIDS Mathematical Model of Triangle Transmission
title_full HIV/AIDS Mathematical Model of Triangle Transmission
title_fullStr HIV/AIDS Mathematical Model of Triangle Transmission
title_full_unstemmed HIV/AIDS Mathematical Model of Triangle Transmission
title_short HIV/AIDS Mathematical Model of Triangle Transmission
title_sort hiv/aids mathematical model of triangle transmission
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786322/
https://www.ncbi.nlm.nih.gov/pubmed/36560753
http://dx.doi.org/10.3390/v14122749
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