Cargando…
A Vaccine Targeting Ovine Herpesvirus 2 Glycoprotein B Protects against Sheep-Associated Malignant Catarrhal Fever
Malignant catarrhal fever (MCF) is a complex and often fatal disease of ungulates. Effective vaccines are needed to avoid MCF outbreaks and mitigate losses. This study aimed to evaluate a sheep-associated MCF (SA-MCF) vaccine candidate targeting ovine herpesvirus 2 (OvHV-2) glycoprotein B (gB). Rabb...
Autores principales: | Cunha, Cristina W., Baker, Katherine N., O’Toole, Donal, Cole, Emily, Shringi, Smriti, Dewals, Benjamin G., Vanderplasschen, Alain, Li, Hong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786699/ https://www.ncbi.nlm.nih.gov/pubmed/36560568 http://dx.doi.org/10.3390/vaccines10122156 |
Ejemplares similares
-
Replacement of Glycoprotein B in Alcelaphine Herpesvirus 1 by Its Ovine Herpesvirus 2 Homolog : Implications in Vaccine Development for Sheep-Associated Malignant Catarrhal Fever
por: Cunha, Cristina W., et al.
Publicado: (2016) -
OvHV-2 Glycoprotein B Delivered by a Recombinant BoHV-4 Is Immunogenic and Induces Partial Protection against Sheep-Associated Malignant Catarrhal Fever in a Rabbit Model
por: Shringi, Smriti, et al.
Publicado: (2021) -
Malignant Catarrhal Fever Induced by Alcelaphine herpesvirus 1 Is Associated with Proliferation of CD8(+) T Cells Supporting a Latent Infection
por: Dewals, Benjamin, et al.
Publicado: (2008) -
Malignant catarrhal fever induced by Alcelaphine herpesvirus 1 is characterized by an expansion of activated CD3(+)CD8(+)CD4(- )T cells expressing a cytotoxic phenotype in both lymphoid and non-lymphoid tissues
por: Dewals, Benjamin G, et al.
Publicado: (2011) -
Alcelaphine herpesvirus 1 genes A7 and A8 regulate viral spread and are essential for malignant catarrhal fever
por: Myster, Françoise, et al.
Publicado: (2020)