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Maslinic Acid: A New Compound for the Treatment of Multiple Organ Diseases
Maslinic acid (MA) is a pentacyclic triterpene acid, which exists in many plants, including olive, and is highly safe for human beings. In recent years, it has been reported that MA has anti-inflammatory, antioxidant, anti-tumor, hypoglycemic, neuroprotective and other biological activities. More an...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786823/ https://www.ncbi.nlm.nih.gov/pubmed/36557864 http://dx.doi.org/10.3390/molecules27248732 |
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author | He, Yan Wang, Yi Yang, Kun Jiao, Jia Zhan, Hong Yang, Youjun Lv, De Li, Weihong Ding, Weijun |
author_facet | He, Yan Wang, Yi Yang, Kun Jiao, Jia Zhan, Hong Yang, Youjun Lv, De Li, Weihong Ding, Weijun |
author_sort | He, Yan |
collection | PubMed |
description | Maslinic acid (MA) is a pentacyclic triterpene acid, which exists in many plants, including olive, and is highly safe for human beings. In recent years, it has been reported that MA has anti-inflammatory, antioxidant, anti-tumor, hypoglycemic, neuroprotective and other biological activities. More and more experimental data has shown that MA has a good therapeutic effect on multiple organ diseases, indicating that it has great clinical application potential. In this paper, the extraction, purification, identification and analysis, biological activity, pharmacokinetics in vivo and molecular mechanism of MA in treating various organ diseases are reviewed. It is hoped to provide a new idea for MA to treat various organ diseases. |
format | Online Article Text |
id | pubmed-9786823 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97868232022-12-24 Maslinic Acid: A New Compound for the Treatment of Multiple Organ Diseases He, Yan Wang, Yi Yang, Kun Jiao, Jia Zhan, Hong Yang, Youjun Lv, De Li, Weihong Ding, Weijun Molecules Review Maslinic acid (MA) is a pentacyclic triterpene acid, which exists in many plants, including olive, and is highly safe for human beings. In recent years, it has been reported that MA has anti-inflammatory, antioxidant, anti-tumor, hypoglycemic, neuroprotective and other biological activities. More and more experimental data has shown that MA has a good therapeutic effect on multiple organ diseases, indicating that it has great clinical application potential. In this paper, the extraction, purification, identification and analysis, biological activity, pharmacokinetics in vivo and molecular mechanism of MA in treating various organ diseases are reviewed. It is hoped to provide a new idea for MA to treat various organ diseases. MDPI 2022-12-09 /pmc/articles/PMC9786823/ /pubmed/36557864 http://dx.doi.org/10.3390/molecules27248732 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review He, Yan Wang, Yi Yang, Kun Jiao, Jia Zhan, Hong Yang, Youjun Lv, De Li, Weihong Ding, Weijun Maslinic Acid: A New Compound for the Treatment of Multiple Organ Diseases |
title | Maslinic Acid: A New Compound for the Treatment of Multiple Organ Diseases |
title_full | Maslinic Acid: A New Compound for the Treatment of Multiple Organ Diseases |
title_fullStr | Maslinic Acid: A New Compound for the Treatment of Multiple Organ Diseases |
title_full_unstemmed | Maslinic Acid: A New Compound for the Treatment of Multiple Organ Diseases |
title_short | Maslinic Acid: A New Compound for the Treatment of Multiple Organ Diseases |
title_sort | maslinic acid: a new compound for the treatment of multiple organ diseases |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786823/ https://www.ncbi.nlm.nih.gov/pubmed/36557864 http://dx.doi.org/10.3390/molecules27248732 |
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