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Extended Applications of Small-Molecule Covalent Inhibitors toward Novel Therapeutic Targets
Recently, small-molecule covalent inhibitors have been accepted as a practical tool for targeting previously “undruggable” proteins. The high target selectivity of modern covalent inhibitors is now alleviating toxicity concerns regarding the covalent modifications of proteins. However, despite the t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786830/ https://www.ncbi.nlm.nih.gov/pubmed/36558928 http://dx.doi.org/10.3390/ph15121478 |