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Extended Applications of Small-Molecule Covalent Inhibitors toward Novel Therapeutic Targets

Recently, small-molecule covalent inhibitors have been accepted as a practical tool for targeting previously “undruggable” proteins. The high target selectivity of modern covalent inhibitors is now alleviating toxicity concerns regarding the covalent modifications of proteins. However, despite the t...

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Detalles Bibliográficos
Autores principales: Lee, Jesang, Park, Seung Bum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786830/
https://www.ncbi.nlm.nih.gov/pubmed/36558928
http://dx.doi.org/10.3390/ph15121478