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Relating self‐disorders to neurocognitive and psychopathological measures in first‐episode schizophrenia

AIM: The notion of a disturbed self as the core feature of schizophrenia dates back to the founding texts on the illness. Since the development of the psychometric tool for examination of anomalous self‐experience (EASE), self‐disorders have become accessible to empirical research. Empirical studies...

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Autores principales: Sandsten, Karl Erik, Wainio‐Theberge, Soren, Nordgaard, Julie, Kjaer, Troels Wesenberg, Northoff, Georg, Parnas, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Publishing Asia Pty Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786869/
https://www.ncbi.nlm.nih.gov/pubmed/35081668
http://dx.doi.org/10.1111/eip.13269
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author Sandsten, Karl Erik
Wainio‐Theberge, Soren
Nordgaard, Julie
Kjaer, Troels Wesenberg
Northoff, Georg
Parnas, Josef
author_facet Sandsten, Karl Erik
Wainio‐Theberge, Soren
Nordgaard, Julie
Kjaer, Troels Wesenberg
Northoff, Georg
Parnas, Josef
author_sort Sandsten, Karl Erik
collection PubMed
description AIM: The notion of a disturbed self as the core feature of schizophrenia dates back to the founding texts on the illness. Since the development of the psychometric tool for examination of anomalous self‐experience (EASE), self‐disorders have become accessible to empirical research. Empirical studies have shown that EASE measured self‐disorders predict schizophrenia spectrum in prospective studies and consistently show a selective hyper aggregation of self‐disorder in schizophrenia and schizotypal disorders. The aim of this study is to investigate the relationship between self‐disorders cognitive deficits and symptoms in schizophrenia. METHODS: Thirty‐five non‐acute first‐episode patients with schizophrenia and 35 matched healthy controls were evaluated with EASE, cognitive deficits, and symptoms (PANSS positive, negative and general). [Correction added on 28 January 2022, after first online publication: the words, ‘evaluated with’ were missing and have now been added to the preceding sentence.] RESULTS: The results show that self‐disorders and symptoms are correlated among patients with schizophrenia, but not with cognitive deficits. Moreover, with the exception of attentional deficits, neurocognitive impairment was not significantly higher among patients with schizophrenia compared to healthy controls. CONCLUSIONS: We argue that this adds support to a view of schizophrenia as being characterized by specific traits of pre‐reflective self‐disturbance, which are related to the severity of symptoms, whereas neurocognitive impairment reflects a separate or distinct aspect of schizophrenia.
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spelling pubmed-97868692022-12-27 Relating self‐disorders to neurocognitive and psychopathological measures in first‐episode schizophrenia Sandsten, Karl Erik Wainio‐Theberge, Soren Nordgaard, Julie Kjaer, Troels Wesenberg Northoff, Georg Parnas, Josef Early Interv Psychiatry Original Articles AIM: The notion of a disturbed self as the core feature of schizophrenia dates back to the founding texts on the illness. Since the development of the psychometric tool for examination of anomalous self‐experience (EASE), self‐disorders have become accessible to empirical research. Empirical studies have shown that EASE measured self‐disorders predict schizophrenia spectrum in prospective studies and consistently show a selective hyper aggregation of self‐disorder in schizophrenia and schizotypal disorders. The aim of this study is to investigate the relationship between self‐disorders cognitive deficits and symptoms in schizophrenia. METHODS: Thirty‐five non‐acute first‐episode patients with schizophrenia and 35 matched healthy controls were evaluated with EASE, cognitive deficits, and symptoms (PANSS positive, negative and general). [Correction added on 28 January 2022, after first online publication: the words, ‘evaluated with’ were missing and have now been added to the preceding sentence.] RESULTS: The results show that self‐disorders and symptoms are correlated among patients with schizophrenia, but not with cognitive deficits. Moreover, with the exception of attentional deficits, neurocognitive impairment was not significantly higher among patients with schizophrenia compared to healthy controls. CONCLUSIONS: We argue that this adds support to a view of schizophrenia as being characterized by specific traits of pre‐reflective self‐disturbance, which are related to the severity of symptoms, whereas neurocognitive impairment reflects a separate or distinct aspect of schizophrenia. Wiley Publishing Asia Pty Ltd 2022-01-26 2022-11 /pmc/articles/PMC9786869/ /pubmed/35081668 http://dx.doi.org/10.1111/eip.13269 Text en © 2022 The Authors. Early Intervention in Psychiatry published by John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Sandsten, Karl Erik
Wainio‐Theberge, Soren
Nordgaard, Julie
Kjaer, Troels Wesenberg
Northoff, Georg
Parnas, Josef
Relating self‐disorders to neurocognitive and psychopathological measures in first‐episode schizophrenia
title Relating self‐disorders to neurocognitive and psychopathological measures in first‐episode schizophrenia
title_full Relating self‐disorders to neurocognitive and psychopathological measures in first‐episode schizophrenia
title_fullStr Relating self‐disorders to neurocognitive and psychopathological measures in first‐episode schizophrenia
title_full_unstemmed Relating self‐disorders to neurocognitive and psychopathological measures in first‐episode schizophrenia
title_short Relating self‐disorders to neurocognitive and psychopathological measures in first‐episode schizophrenia
title_sort relating self‐disorders to neurocognitive and psychopathological measures in first‐episode schizophrenia
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9786869/
https://www.ncbi.nlm.nih.gov/pubmed/35081668
http://dx.doi.org/10.1111/eip.13269
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