Cargando…
Identification of the Major Degradation Pathways of Selumetinib
Selumetinib is administered orally in capsule form and is indicated for the treatment of neurofibromatosis. To facilitate dosage adjustments, liquid preparations, such as solutions or suspensions, are to be developed. This led, first, to determine the stability profile of soluble or dispersed selume...
Autores principales: | Bouchema, Tahar Sif eddine, Annereau, Maxime, Vieillard, Victoire, Boquet, Raphael, Coelho, Gisele Abreu, Castelli, Florence, Solgadi, Audrey, Paul, Muriel, Yagoubi, Najet, Secretan, Philippe-Henri, Do, Bernard |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787286/ https://www.ncbi.nlm.nih.gov/pubmed/36559146 http://dx.doi.org/10.3390/pharmaceutics14122651 |
Ejemplares similares
-
Evolution of the Chronic Venous Leg Ulcer Microenvironment and Its Impact on Medical Devices and Wound Care Therapies
por: Coelho, Gisele Abreu, et al.
Publicado: (2023) -
Unequal Behaviour between Hydrolysable Functions of Nirmatrelvir under Stress Conditions: Structural and Theoretical Approaches in Support of Preformulation Studies
por: Secretan, Philippe-Henri, et al.
Publicado: (2022) -
3D-Printed, Liquid-Filled Capsules of Concentrated and Stabilized Polyphenol Epigallocatechin Gallate, Developed in a Clinical Trial
por: Secretan, Philippe-Henri, et al.
Publicado: (2023) -
Molecular Mechanisms Involved in the Chemical Instability of ONC201 and Methods to Counter Its Degradation in Solution
por: Annereau, Maxime, et al.
Publicado: (2023) -
Mechanical Performance and Cytotoxicity of an Alginate/Polyacrylamide Bipolymer Network Developed for Medical Applications
por: Mouchati, Abdullah, et al.
Publicado: (2023)