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Time of day influences stress hormone response to ketamine

Over 50% of depressed patients show hyperactivity of the hypothalamic–pituitary–adrenal (HPA) axis. Conventional therapy takes weeks to months to improve symptoms. Ketamine has rapid onset antidepressant effects. Yet its action on HPA axis activity is poorly understood. Here, we measured the cortico...

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Detalles Bibliográficos
Autores principales:	Birnie, Matthew T., Eapen, Alen V., Kershaw, Yvonne M., Lodge, David, Collingridge, Graham L., Conway‐Campbell, Becky L., Lightman, Stafford L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Fundamental and Mechanistic Neuroendocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787621/ https://www.ncbi.nlm.nih.gov/pubmed/36056546 http://dx.doi.org/10.1111/jne.13194

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