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Recent Advances in Natural Polyphenol Research

Polyphenols are secondary metabolites produced by plants, which contribute to the plant’s defense against abiotic stress conditions (e.g., UV radiation and precipitation), the aggression of herbivores, and plant pathogens. Epidemiological studies suggest that long-term consumption of plant polypheno...

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Detalles Bibliográficos
Autores principales: Dini, Irene, Grumetto, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787743/
https://www.ncbi.nlm.nih.gov/pubmed/36557912
http://dx.doi.org/10.3390/molecules27248777
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author Dini, Irene
Grumetto, Lucia
author_facet Dini, Irene
Grumetto, Lucia
author_sort Dini, Irene
collection PubMed
description Polyphenols are secondary metabolites produced by plants, which contribute to the plant’s defense against abiotic stress conditions (e.g., UV radiation and precipitation), the aggression of herbivores, and plant pathogens. Epidemiological studies suggest that long-term consumption of plant polyphenols protects against cardiovascular disease, cancer, osteoporosis, diabetes, and neurodegenerative diseases. Their structural diversity has fascinated and confronted analytical chemists on how to carry out unambiguous identification, exhaustive recovery from plants and organic waste, and define their nutritional and biological potential. The food, cosmetic, and pharmaceutical industries employ polyphenols from fruits and vegetables to produce additives, additional foods, and supplements. In some cases, nanocarriers have been used to protect polyphenols during food processing, to solve the issues related to low water solubility, to transport them to the site of action, and improve their bioavailability. This review summarizes the structure-bioactivity relationships, processing parameters that impact polyphenol stability and bioavailability, the research progress in nanocarrier delivery, and the most innovative methodologies for the exhaustive recovery of polyphenols from plant and agri-waste materials.
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spelling pubmed-97877432022-12-24 Recent Advances in Natural Polyphenol Research Dini, Irene Grumetto, Lucia Molecules Review Polyphenols are secondary metabolites produced by plants, which contribute to the plant’s defense against abiotic stress conditions (e.g., UV radiation and precipitation), the aggression of herbivores, and plant pathogens. Epidemiological studies suggest that long-term consumption of plant polyphenols protects against cardiovascular disease, cancer, osteoporosis, diabetes, and neurodegenerative diseases. Their structural diversity has fascinated and confronted analytical chemists on how to carry out unambiguous identification, exhaustive recovery from plants and organic waste, and define their nutritional and biological potential. The food, cosmetic, and pharmaceutical industries employ polyphenols from fruits and vegetables to produce additives, additional foods, and supplements. In some cases, nanocarriers have been used to protect polyphenols during food processing, to solve the issues related to low water solubility, to transport them to the site of action, and improve their bioavailability. This review summarizes the structure-bioactivity relationships, processing parameters that impact polyphenol stability and bioavailability, the research progress in nanocarrier delivery, and the most innovative methodologies for the exhaustive recovery of polyphenols from plant and agri-waste materials. MDPI 2022-12-11 /pmc/articles/PMC9787743/ /pubmed/36557912 http://dx.doi.org/10.3390/molecules27248777 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Dini, Irene
Grumetto, Lucia
Recent Advances in Natural Polyphenol Research
title Recent Advances in Natural Polyphenol Research
title_full Recent Advances in Natural Polyphenol Research
title_fullStr Recent Advances in Natural Polyphenol Research
title_full_unstemmed Recent Advances in Natural Polyphenol Research
title_short Recent Advances in Natural Polyphenol Research
title_sort recent advances in natural polyphenol research
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787743/
https://www.ncbi.nlm.nih.gov/pubmed/36557912
http://dx.doi.org/10.3390/molecules27248777
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