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Adherence to adjuvant endocrine therapy among White British and ethnic minority breast cancer survivors in the United Kingdom
OBJECTIVE: Around half of women do not take adjuvant endocrine therapy (AET) as prescribed. Research suggests that adherence rates vary across ethnic groups. This study compared AET adherences rates in White British women and women from minority ethnic groups in the United Kingdom. METHODS: This is...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787781/ https://www.ncbi.nlm.nih.gov/pubmed/36255032 http://dx.doi.org/10.1111/ecc.13722 |
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author | McGuinness, Serena Hughes, Lyndsay Moss‐Morris, Rona Hunter, Myra Norton, Sam Moon, Zoe |
author_facet | McGuinness, Serena Hughes, Lyndsay Moss‐Morris, Rona Hunter, Myra Norton, Sam Moon, Zoe |
author_sort | McGuinness, Serena |
collection | PubMed |
description | OBJECTIVE: Around half of women do not take adjuvant endocrine therapy (AET) as prescribed. Research suggests that adherence rates vary across ethnic groups. This study compared AET adherences rates in White British women and women from minority ethnic groups in the United Kingdom. METHODS: This is an observational study with 2001 breast cancer survivors recruited from outpatient clinics. Eligible women were diagnosed with primary breast cancer and prescribed AET within the last 3 years. Adherence was measured using the Medication Adherence Rating Scale. Eligible women were asked to complete a questionnaire pack that collected sociodemographic data such as age, relationship status and ethnicity. Independent samples t tests and χ (2) tests were used to compare White British women and women from minority ethnic groups on self‐reported adherence to AET. RESULTS: Of White British women, 27.8% were classed as non‐adherent, compared to 44.4% of women from minority ethnic groups. A logistic regression controlling for relevant demographics indicated that women from minority ethnic groups had a significantly higher risk of non‐adherence than women who were White British (odds ratio = 1.50, p = 0.03) CONCLUSION: Rates of non‐adherence to AET are higher in women from minority ethnic groups, which may contribute towards racial disparities in breast cancer outcomes. Research with larger and more diverse samples is needed to explore this further and to investigate the psychosocial factors driving differences in adherence. |
format | Online Article Text |
id | pubmed-9787781 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-97877812022-12-28 Adherence to adjuvant endocrine therapy among White British and ethnic minority breast cancer survivors in the United Kingdom McGuinness, Serena Hughes, Lyndsay Moss‐Morris, Rona Hunter, Myra Norton, Sam Moon, Zoe Eur J Cancer Care (Engl) Original Articles OBJECTIVE: Around half of women do not take adjuvant endocrine therapy (AET) as prescribed. Research suggests that adherence rates vary across ethnic groups. This study compared AET adherences rates in White British women and women from minority ethnic groups in the United Kingdom. METHODS: This is an observational study with 2001 breast cancer survivors recruited from outpatient clinics. Eligible women were diagnosed with primary breast cancer and prescribed AET within the last 3 years. Adherence was measured using the Medication Adherence Rating Scale. Eligible women were asked to complete a questionnaire pack that collected sociodemographic data such as age, relationship status and ethnicity. Independent samples t tests and χ (2) tests were used to compare White British women and women from minority ethnic groups on self‐reported adherence to AET. RESULTS: Of White British women, 27.8% were classed as non‐adherent, compared to 44.4% of women from minority ethnic groups. A logistic regression controlling for relevant demographics indicated that women from minority ethnic groups had a significantly higher risk of non‐adherence than women who were White British (odds ratio = 1.50, p = 0.03) CONCLUSION: Rates of non‐adherence to AET are higher in women from minority ethnic groups, which may contribute towards racial disparities in breast cancer outcomes. Research with larger and more diverse samples is needed to explore this further and to investigate the psychosocial factors driving differences in adherence. John Wiley and Sons Inc. 2022-10-18 2022-11 /pmc/articles/PMC9787781/ /pubmed/36255032 http://dx.doi.org/10.1111/ecc.13722 Text en © 2022 The Authors. European Journal of Cancer Care published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles McGuinness, Serena Hughes, Lyndsay Moss‐Morris, Rona Hunter, Myra Norton, Sam Moon, Zoe Adherence to adjuvant endocrine therapy among White British and ethnic minority breast cancer survivors in the United Kingdom |
title | Adherence to adjuvant endocrine therapy among White British and ethnic minority breast cancer survivors in the United Kingdom |
title_full | Adherence to adjuvant endocrine therapy among White British and ethnic minority breast cancer survivors in the United Kingdom |
title_fullStr | Adherence to adjuvant endocrine therapy among White British and ethnic minority breast cancer survivors in the United Kingdom |
title_full_unstemmed | Adherence to adjuvant endocrine therapy among White British and ethnic minority breast cancer survivors in the United Kingdom |
title_short | Adherence to adjuvant endocrine therapy among White British and ethnic minority breast cancer survivors in the United Kingdom |
title_sort | adherence to adjuvant endocrine therapy among white british and ethnic minority breast cancer survivors in the united kingdom |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787781/ https://www.ncbi.nlm.nih.gov/pubmed/36255032 http://dx.doi.org/10.1111/ecc.13722 |
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