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Adherence to Pro-Vegetarian Food Patterns and Risk of Oesophagus, Stomach, and Pancreas Cancers: A Multi Case–Control Study (The PANESOES Study)

We aimed to evaluate the association between three previously defined pro-vegetarian (PVG) food patterns and the cancers of the oesophagus, stomach, and pancreas in a multi case–control study. We analyzed data from a multi-case hospital-based study carried out in two Mediterranean provinces in Spain...

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Autores principales: Oncina-Cánovas, Alejandro, González-Palacios, Sandra, Notario-Barandiaran, Leyre, Torres-Collado, Laura, Signes-Pastor, Antonio, de-Madaria, Enrique, Santibañez, Miguel, García-de la Hera, Manuela, Vioque, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787989/
https://www.ncbi.nlm.nih.gov/pubmed/36558447
http://dx.doi.org/10.3390/nu14245288
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author Oncina-Cánovas, Alejandro
González-Palacios, Sandra
Notario-Barandiaran, Leyre
Torres-Collado, Laura
Signes-Pastor, Antonio
de-Madaria, Enrique
Santibañez, Miguel
García-de la Hera, Manuela
Vioque, Jesús
author_facet Oncina-Cánovas, Alejandro
González-Palacios, Sandra
Notario-Barandiaran, Leyre
Torres-Collado, Laura
Signes-Pastor, Antonio
de-Madaria, Enrique
Santibañez, Miguel
García-de la Hera, Manuela
Vioque, Jesús
author_sort Oncina-Cánovas, Alejandro
collection PubMed
description We aimed to evaluate the association between three previously defined pro-vegetarian (PVG) food patterns and the cancers of the oesophagus, stomach, and pancreas in a multi case–control study. We analyzed data from a multi-case hospital-based study carried out in two Mediterranean provinces in Spain. A total of 1233 participants were included in the analyses: 778 incident cancer cases, histologically confirmed (199 oesophagus, 414 stomach, and 165 pancreas) and 455 controls. A dietary assessment was performed using a validated food frequency questionnaire (FFQ). Three PVG food patterns (general, healthful, and unhealthful) were estimated using 12 food groups for the general PVG (gPVG), scoring positive plant-based foods and negative animal-based foods, and 18 food groups, for the healthful (hPVG) and unhealthful (uPVG) food patterns. Multinomial logistic regression was used to estimate relative risk ratios (RRR) and confidence intervals (95% CI) for quintiles of adherence to PVG patterns and as a continuous variable. The RRR (95% CI) for the highest vs. the lowest quintile of gPVG were, RRR = 0.37 (0.32, 0.42) for the oesophagus, RRR = 0.34 (0.27, 0.43) for the stomach, and RRR = 0.43 (0.35, 0.52) for pancreas cancer. For the hPVG, the RRR were RRR = 0.72 (0.58, 0.90) for the oesophagus, RRR = 0.42 (0.34, 0.52) for the stomach, and RRR = 0.74 (0.59, 0.92) for pancreas cancer. The uPVG was associated with a higher risk of stomach cancer RRR = 1.76 (1.42, 2.18). Higher adherence to gPVG and hPVG food patterns is associated with a lower risk of oesophageal, stomach, and pancreas cancers, while a higher adherence to a uPVG food pattern is associated with a higher risk of stomach cancer.
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spelling pubmed-97879892022-12-24 Adherence to Pro-Vegetarian Food Patterns and Risk of Oesophagus, Stomach, and Pancreas Cancers: A Multi Case–Control Study (The PANESOES Study) Oncina-Cánovas, Alejandro González-Palacios, Sandra Notario-Barandiaran, Leyre Torres-Collado, Laura Signes-Pastor, Antonio de-Madaria, Enrique Santibañez, Miguel García-de la Hera, Manuela Vioque, Jesús Nutrients Article We aimed to evaluate the association between three previously defined pro-vegetarian (PVG) food patterns and the cancers of the oesophagus, stomach, and pancreas in a multi case–control study. We analyzed data from a multi-case hospital-based study carried out in two Mediterranean provinces in Spain. A total of 1233 participants were included in the analyses: 778 incident cancer cases, histologically confirmed (199 oesophagus, 414 stomach, and 165 pancreas) and 455 controls. A dietary assessment was performed using a validated food frequency questionnaire (FFQ). Three PVG food patterns (general, healthful, and unhealthful) were estimated using 12 food groups for the general PVG (gPVG), scoring positive plant-based foods and negative animal-based foods, and 18 food groups, for the healthful (hPVG) and unhealthful (uPVG) food patterns. Multinomial logistic regression was used to estimate relative risk ratios (RRR) and confidence intervals (95% CI) for quintiles of adherence to PVG patterns and as a continuous variable. The RRR (95% CI) for the highest vs. the lowest quintile of gPVG were, RRR = 0.37 (0.32, 0.42) for the oesophagus, RRR = 0.34 (0.27, 0.43) for the stomach, and RRR = 0.43 (0.35, 0.52) for pancreas cancer. For the hPVG, the RRR were RRR = 0.72 (0.58, 0.90) for the oesophagus, RRR = 0.42 (0.34, 0.52) for the stomach, and RRR = 0.74 (0.59, 0.92) for pancreas cancer. The uPVG was associated with a higher risk of stomach cancer RRR = 1.76 (1.42, 2.18). Higher adherence to gPVG and hPVG food patterns is associated with a lower risk of oesophageal, stomach, and pancreas cancers, while a higher adherence to a uPVG food pattern is associated with a higher risk of stomach cancer. MDPI 2022-12-12 /pmc/articles/PMC9787989/ /pubmed/36558447 http://dx.doi.org/10.3390/nu14245288 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Oncina-Cánovas, Alejandro
González-Palacios, Sandra
Notario-Barandiaran, Leyre
Torres-Collado, Laura
Signes-Pastor, Antonio
de-Madaria, Enrique
Santibañez, Miguel
García-de la Hera, Manuela
Vioque, Jesús
Adherence to Pro-Vegetarian Food Patterns and Risk of Oesophagus, Stomach, and Pancreas Cancers: A Multi Case–Control Study (The PANESOES Study)
title Adherence to Pro-Vegetarian Food Patterns and Risk of Oesophagus, Stomach, and Pancreas Cancers: A Multi Case–Control Study (The PANESOES Study)
title_full Adherence to Pro-Vegetarian Food Patterns and Risk of Oesophagus, Stomach, and Pancreas Cancers: A Multi Case–Control Study (The PANESOES Study)
title_fullStr Adherence to Pro-Vegetarian Food Patterns and Risk of Oesophagus, Stomach, and Pancreas Cancers: A Multi Case–Control Study (The PANESOES Study)
title_full_unstemmed Adherence to Pro-Vegetarian Food Patterns and Risk of Oesophagus, Stomach, and Pancreas Cancers: A Multi Case–Control Study (The PANESOES Study)
title_short Adherence to Pro-Vegetarian Food Patterns and Risk of Oesophagus, Stomach, and Pancreas Cancers: A Multi Case–Control Study (The PANESOES Study)
title_sort adherence to pro-vegetarian food patterns and risk of oesophagus, stomach, and pancreas cancers: a multi case–control study (the panesoes study)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9787989/
https://www.ncbi.nlm.nih.gov/pubmed/36558447
http://dx.doi.org/10.3390/nu14245288
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