Citrullination is linked to reduced Ca(2+) sensitivity in hearts of a murine model of rheumatoid arthritis

AIMS: Cardiac contractile dysfunction is prevalent in rheumatoid arthritis (RA), with an increased risk for heart failure. A hallmark of RA has increased levels of peptidyl arginine deaminases (PAD) that convert arginine to citrulline leading to ubiquitous citrullination, including in the heart. We...

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Detalles Bibliográficos
Autores principales: Pironti, Gianluigi, Gastaldello, Stefano, Rassier, Dilson E., Lanner, Johanna T., Carlström, Mattias, Lund, Lars H., Westerblad, Håkan, Yamada, Takashi, Andersson, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788013/
https://www.ncbi.nlm.nih.gov/pubmed/36002394
http://dx.doi.org/10.1111/apha.13869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788013/
https://www.ncbi.nlm.nih.gov/pubmed/36002394
http://dx.doi.org/10.1111/apha.13869

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