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Emergence of High Pathogenicity Avian Influenza Virus H5N1 Clade 2.3.4.4b in Wild Birds and Poultry in Botswana
Numerous outbreaks of high-pathogenicity avian influenza (HPAI) were reported during 2020–2021. In Africa, H5Nx has been detected in Benin, Burkina Faso, Nigeria, Senegal, Lesotho, Namibia and South Africa in both wild birds and poultry. Botswana reported its first outbreak of HPAI to the World Orga...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788244/ https://www.ncbi.nlm.nih.gov/pubmed/36560605 http://dx.doi.org/10.3390/v14122601 |
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| author | Letsholo, Samantha L. James, Joe Meyer, Stephanie M. Byrne, Alexander M. P. Reid, Scott M. Settypalli, Tirumala B. K. Datta, Sneha Oarabile, Letlhogile Kemolatlhe, Obakeng Pebe, Kgakgamatso T. Mafonko, Bruce R. Kgotlele, Tebogo J. Kumile, Kago Modise, Boitumelo Thanda, Carter Nyange, John F. C. Marobela-Raborokgwe, Chandapiwa Cattoli, Giovanni Lamien, Charles E. Brown, Ian H. Dundon, William G. Banyard, Ashley C. |
| author_facet | Letsholo, Samantha L. James, Joe Meyer, Stephanie M. Byrne, Alexander M. P. Reid, Scott M. Settypalli, Tirumala B. K. Datta, Sneha Oarabile, Letlhogile Kemolatlhe, Obakeng Pebe, Kgakgamatso T. Mafonko, Bruce R. Kgotlele, Tebogo J. Kumile, Kago Modise, Boitumelo Thanda, Carter Nyange, John F. C. Marobela-Raborokgwe, Chandapiwa Cattoli, Giovanni Lamien, Charles E. Brown, Ian H. Dundon, William G. Banyard, Ashley C. |
| author_sort | Letsholo, Samantha L. |
| collection | PubMed |
| description | Numerous outbreaks of high-pathogenicity avian influenza (HPAI) were reported during 2020–2021. In Africa, H5Nx has been detected in Benin, Burkina Faso, Nigeria, Senegal, Lesotho, Namibia and South Africa in both wild birds and poultry. Botswana reported its first outbreak of HPAI to the World Organisation for Animal Health (WOAH) in 2021. An H5N1 virus was detected in a fish eagle, doves, and chickens. Full genome sequence analysis revealed that the virus belonged to clade 2.3.4.4b and showed high identity within haemagglutinin (HA) and neuraminidase proteins (NA) for viruses identified across a geographically broad range of locations. The detection of H5N1 in Botswana has important implications for disease management, wild bird conservation, tourism, public health, economic empowerment of vulnerable communities and food security in the region. |
| format | Online Article Text |
| id | pubmed-9788244 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-97882442022-12-24 Emergence of High Pathogenicity Avian Influenza Virus H5N1 Clade 2.3.4.4b in Wild Birds and Poultry in Botswana Letsholo, Samantha L. James, Joe Meyer, Stephanie M. Byrne, Alexander M. P. Reid, Scott M. Settypalli, Tirumala B. K. Datta, Sneha Oarabile, Letlhogile Kemolatlhe, Obakeng Pebe, Kgakgamatso T. Mafonko, Bruce R. Kgotlele, Tebogo J. Kumile, Kago Modise, Boitumelo Thanda, Carter Nyange, John F. C. Marobela-Raborokgwe, Chandapiwa Cattoli, Giovanni Lamien, Charles E. Brown, Ian H. Dundon, William G. Banyard, Ashley C. Viruses Communication Numerous outbreaks of high-pathogenicity avian influenza (HPAI) were reported during 2020–2021. In Africa, H5Nx has been detected in Benin, Burkina Faso, Nigeria, Senegal, Lesotho, Namibia and South Africa in both wild birds and poultry. Botswana reported its first outbreak of HPAI to the World Organisation for Animal Health (WOAH) in 2021. An H5N1 virus was detected in a fish eagle, doves, and chickens. Full genome sequence analysis revealed that the virus belonged to clade 2.3.4.4b and showed high identity within haemagglutinin (HA) and neuraminidase proteins (NA) for viruses identified across a geographically broad range of locations. The detection of H5N1 in Botswana has important implications for disease management, wild bird conservation, tourism, public health, economic empowerment of vulnerable communities and food security in the region. MDPI 2022-11-22 /pmc/articles/PMC9788244/ /pubmed/36560605 http://dx.doi.org/10.3390/v14122601 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Communication Letsholo, Samantha L. James, Joe Meyer, Stephanie M. Byrne, Alexander M. P. Reid, Scott M. Settypalli, Tirumala B. K. Datta, Sneha Oarabile, Letlhogile Kemolatlhe, Obakeng Pebe, Kgakgamatso T. Mafonko, Bruce R. Kgotlele, Tebogo J. Kumile, Kago Modise, Boitumelo Thanda, Carter Nyange, John F. C. Marobela-Raborokgwe, Chandapiwa Cattoli, Giovanni Lamien, Charles E. Brown, Ian H. Dundon, William G. Banyard, Ashley C. Emergence of High Pathogenicity Avian Influenza Virus H5N1 Clade 2.3.4.4b in Wild Birds and Poultry in Botswana |
| title | Emergence of High Pathogenicity Avian Influenza Virus H5N1 Clade 2.3.4.4b in Wild Birds and Poultry in Botswana |
| title_full | Emergence of High Pathogenicity Avian Influenza Virus H5N1 Clade 2.3.4.4b in Wild Birds and Poultry in Botswana |
| title_fullStr | Emergence of High Pathogenicity Avian Influenza Virus H5N1 Clade 2.3.4.4b in Wild Birds and Poultry in Botswana |
| title_full_unstemmed | Emergence of High Pathogenicity Avian Influenza Virus H5N1 Clade 2.3.4.4b in Wild Birds and Poultry in Botswana |
| title_short | Emergence of High Pathogenicity Avian Influenza Virus H5N1 Clade 2.3.4.4b in Wild Birds and Poultry in Botswana |
| title_sort | emergence of high pathogenicity avian influenza virus h5n1 clade 2.3.4.4b in wild birds and poultry in botswana |
| topic | Communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788244/ https://www.ncbi.nlm.nih.gov/pubmed/36560605 http://dx.doi.org/10.3390/v14122601 |
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