The elegant complexity of fear in non-human animals

Activation of the fear system is adaptive, and protects individuals from impending harm; yet, exacerbation of the fear system is at the source of anxiety-related disorders. Here, we briefly review the ‘why’ and ‘how’ of fear, with an emphasis on models that encapsulate the elegant complexity of rode...

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Detalles Bibliográficos
Autores principales: Monfils, Marie-H., Domjan, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788375/
https://www.ncbi.nlm.nih.gov/pubmed/36069657
http://dx.doi.org/10.1042/ETLS20220001
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author Monfils, Marie-H.
Domjan, Michael
author_facet Monfils, Marie-H.
Domjan, Michael
author_sort Monfils, Marie-H.
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description Activation of the fear system is adaptive, and protects individuals from impending harm; yet, exacerbation of the fear system is at the source of anxiety-related disorders. Here, we briefly review the ‘why’ and ‘how’ of fear, with an emphasis on models that encapsulate the elegant complexity of rodents’ behavioral responding in the face of impending harm, and its relevance to developing treatment interventions.
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spelling pubmed-97883752023-01-06 The elegant complexity of fear in non-human animals Monfils, Marie-H. Domjan, Michael Emerg Top Life Sci Review Articles Activation of the fear system is adaptive, and protects individuals from impending harm; yet, exacerbation of the fear system is at the source of anxiety-related disorders. Here, we briefly review the ‘why’ and ‘how’ of fear, with an emphasis on models that encapsulate the elegant complexity of rodents’ behavioral responding in the face of impending harm, and its relevance to developing treatment interventions. Portland Press Ltd. 2022-09-07 /pmc/articles/PMC9788375/ /pubmed/36069657 http://dx.doi.org/10.1042/ETLS20220001 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Review Articles
Monfils, Marie-H.
Domjan, Michael
The elegant complexity of fear in non-human animals
title The elegant complexity of fear in non-human animals
title_full The elegant complexity of fear in non-human animals
title_fullStr The elegant complexity of fear in non-human animals
title_full_unstemmed The elegant complexity of fear in non-human animals
title_short The elegant complexity of fear in non-human animals
title_sort elegant complexity of fear in non-human animals
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788375/
https://www.ncbi.nlm.nih.gov/pubmed/36069657
http://dx.doi.org/10.1042/ETLS20220001
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