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The pleiotropic roles of eIF5A in cellular life and its therapeutic potential in cancer

Protein synthesis is dysregulated in the majority of cancers and this process therefore provides a good therapeutic target. Many novel anti-cancer agents are directed to target the initiation stage of translation, however, translation elongation also holds great potential as a therapeutic target. Th...

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Detalles Bibliográficos
Autores principales: Sfakianos, Aristeidis Panagiotis, Raven, Rebecca Mallory, Willis, Anne Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788402/
https://www.ncbi.nlm.nih.gov/pubmed/36511302
http://dx.doi.org/10.1042/BST20221035

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