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The pleiotropic roles of eIF5A in cellular life and its therapeutic potential in cancer
Protein synthesis is dysregulated in the majority of cancers and this process therefore provides a good therapeutic target. Many novel anti-cancer agents are directed to target the initiation stage of translation, however, translation elongation also holds great potential as a therapeutic target. Th...
Autores principales: | Sfakianos, Aristeidis Panagiotis, Raven, Rebecca Mallory, Willis, Anne Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788402/ https://www.ncbi.nlm.nih.gov/pubmed/36511302 http://dx.doi.org/10.1042/BST20221035 |
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