Cargando…

The Value of Vaccines: A Tale of Two Parts

Vaccines are essential to ensuring a nation’s health, wellbeing and prosperity. After the coronavirus pandemic commenced, the Australian Government introduced social restrictions to constrain virus transmission, seeing significant economic impacts. Reflecting the extraordinary circumstances, subsequ...

Descripción completa

Detalles Bibliográficos
Autores principales: Fox, Nathan, Adams, Philip, Grainger, David, Herz, Jennifer, Austin, Carolyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788428/
https://www.ncbi.nlm.nih.gov/pubmed/36560467
http://dx.doi.org/10.3390/vaccines10122057
_version_ 1784858752017498112
author Fox, Nathan
Adams, Philip
Grainger, David
Herz, Jennifer
Austin, Carolyn
author_facet Fox, Nathan
Adams, Philip
Grainger, David
Herz, Jennifer
Austin, Carolyn
author_sort Fox, Nathan
collection PubMed
description Vaccines are essential to ensuring a nation’s health, wellbeing and prosperity. After the coronavirus pandemic commenced, the Australian Government introduced social restrictions to constrain virus transmission, seeing significant economic impacts. Reflecting the extraordinary circumstances, subsequent vaccination rollout forwent usual health technology assessment (HTA) processes, facilitating restrictions removal and leading to societal and economic recovery. However, in ‘usual’ circumstances, HTA may not consider such broader effects of vaccines, making it challenging for them to achieve timely funding. We used detailed modelling to compare economic impacts under continued lockdowns against population-wide vaccination rollout between January 2020 and June 2023 and examined global HTA vaccine evaluation methodologies and efforts to develop broader valuation approaches. Australian gross domestic product reduces by approximately AUD 395 billion with lockdowns. With vaccination rollout, this effect is approximately AUD 214bn, a positive incremental impact of AUD 181bn. Vaccination contributes to large estimated positive effects for tourism (AUD 28bn) and education (AUD 26bn) exports, employment (142,000 jobs) and government finances (AUD 259bn). Conversely, global HTA methods generally only consider direct patient health outcomes and healthcare system-related costs, with broader effects usually not impacting funding decisions. Our results suggest that recent efforts to propose broader HTA valuation frameworks warrant further policy consideration.
format Online
Article
Text
id pubmed-9788428
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-97884282022-12-24 The Value of Vaccines: A Tale of Two Parts Fox, Nathan Adams, Philip Grainger, David Herz, Jennifer Austin, Carolyn Vaccines (Basel) Article Vaccines are essential to ensuring a nation’s health, wellbeing and prosperity. After the coronavirus pandemic commenced, the Australian Government introduced social restrictions to constrain virus transmission, seeing significant economic impacts. Reflecting the extraordinary circumstances, subsequent vaccination rollout forwent usual health technology assessment (HTA) processes, facilitating restrictions removal and leading to societal and economic recovery. However, in ‘usual’ circumstances, HTA may not consider such broader effects of vaccines, making it challenging for them to achieve timely funding. We used detailed modelling to compare economic impacts under continued lockdowns against population-wide vaccination rollout between January 2020 and June 2023 and examined global HTA vaccine evaluation methodologies and efforts to develop broader valuation approaches. Australian gross domestic product reduces by approximately AUD 395 billion with lockdowns. With vaccination rollout, this effect is approximately AUD 214bn, a positive incremental impact of AUD 181bn. Vaccination contributes to large estimated positive effects for tourism (AUD 28bn) and education (AUD 26bn) exports, employment (142,000 jobs) and government finances (AUD 259bn). Conversely, global HTA methods generally only consider direct patient health outcomes and healthcare system-related costs, with broader effects usually not impacting funding decisions. Our results suggest that recent efforts to propose broader HTA valuation frameworks warrant further policy consideration. MDPI 2022-11-30 /pmc/articles/PMC9788428/ /pubmed/36560467 http://dx.doi.org/10.3390/vaccines10122057 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fox, Nathan
Adams, Philip
Grainger, David
Herz, Jennifer
Austin, Carolyn
The Value of Vaccines: A Tale of Two Parts
title The Value of Vaccines: A Tale of Two Parts
title_full The Value of Vaccines: A Tale of Two Parts
title_fullStr The Value of Vaccines: A Tale of Two Parts
title_full_unstemmed The Value of Vaccines: A Tale of Two Parts
title_short The Value of Vaccines: A Tale of Two Parts
title_sort value of vaccines: a tale of two parts
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788428/
https://www.ncbi.nlm.nih.gov/pubmed/36560467
http://dx.doi.org/10.3390/vaccines10122057
work_keys_str_mv AT foxnathan thevalueofvaccinesataleoftwoparts
AT adamsphilip thevalueofvaccinesataleoftwoparts
AT graingerdavid thevalueofvaccinesataleoftwoparts
AT herzjennifer thevalueofvaccinesataleoftwoparts
AT austincarolyn thevalueofvaccinesataleoftwoparts
AT foxnathan valueofvaccinesataleoftwoparts
AT adamsphilip valueofvaccinesataleoftwoparts
AT graingerdavid valueofvaccinesataleoftwoparts
AT herzjennifer valueofvaccinesataleoftwoparts
AT austincarolyn valueofvaccinesataleoftwoparts