Cargando…

Formulation of Multicomponent Chrysin-Hydroxy Propyl β Cyclodextrin-Poloxamer Inclusion Complex Using Spray Dry Method: Physicochemical Characterization to Cell Viability Assessment

The work aimed to enhance chrysin (CHR) water solubility, dissolution, and in vitro antibacterial as well as cell viability. Chrysin binary, as well as ternary inclusion complex, were prepared using the spray drying method. The influence of an auxiliary component (poloxamer; PLX) was also assessed a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Imam, Syed Sarim, Alshehri, Sultan, Mahdi, Wael A., Alotaibi, Ahmed M., Alhwaifi, Moath H., Hussain, Afzal, Altamimi, Mohammad A., Qamar, Wajhul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788470/ https://www.ncbi.nlm.nih.gov/pubmed/36558976 http://dx.doi.org/10.3390/ph15121525

Ejemplares similares

Formulation of multicomponent inclusion complex of cyclodextrin-amino acid with Chrysin: Physicochemical characterization, cell viability and apoptosis assessment in human primary glioblastoma cell line
por: Mahdi, Wael A., et al.
Publicado: (2023)

Formulation of Silymarin-β Cyclodextrin-TPGS Inclusion Complex: Physicochemical Characterization, Molecular Docking, and Cell Viability Assessment against Breast Cancer Cell Lines
por: Imam, Syed Sarim, et al.
Publicado: (2023)

Formulation and Evaluation of Luteolin-Loaded Nanovesicles: In Vitro Physicochemical Characterization and Viability Assessment
por: Imam, Syed Sarim, et al.
Publicado: (2021)

Luteolin-Loaded Elastic Liposomes for Transdermal Delivery to Control Breast Cancer: In Vitro and Ex Vivo Evaluations
por: Altamimi, Mohammad A., et al.
Publicado: (2021)

Formulation of Genistein-HP β Cyclodextrin-Poloxamer 188 Ternary Inclusion Complex: Solubility to Cytotoxicity Assessment
por: Zafar, Ameeduzzafar, et al.
Publicado: (2021)

Formulation of Chitosan-Coated Apigenin Bilosomes: In Vitro Characterization, Antimicrobial and Cytotoxicity Assessment
por: Imam, Syed Sarim, et al.
Publicado: (2022)

Masculinizing Effects of Chrysin-Loaded Poloxamer Micelles on Siamese Fighting Fish
por: Khumpirapang, Nattakanwadee, et al.
Publicado: (2021)

Formulation of Piperine–Chitosan-Coated Liposomes: Characterization and In Vitro Cytotoxic Evaluation
por: Imam, Syed Sarim, et al.
Publicado: (2021)

Experimental Design Based Optimization and Ex Vivo Permeation of Desmopressin Acetate Loaded Elastic Liposomes Using Rat Skin
por: Altamimi, Mohammad A., et al.
Publicado: (2021)

Four-Dimensional Printing for Hydrogel: Theoretical Concept, 4D Materials, Shape-Morphing Way, and Future Perspectives
por: Imam, Syed Sarim, et al.
Publicado: (2021)

Cyclodextrin Complexation Improves the Solubility and Caco-2 Permeability of Chrysin
por: Fenyvesi, Ferenc, et al.
Publicado: (2020)

Characterization and Aerosolization Performance of HydroxyPropyl-Beta-Cyclodextrin Particles Produced Using Supercritical Assisted Atomization
por: Wu, Hsien-Tsung, et al.
Publicado: (2021)

Potential of solid dispersions to enhance solubility, bioavailability, and therapeutic efficacy of poorly water-soluble drugs: newer formulation techniques, current marketed scenario and patents
por: Alshehri, Sultan, et al.
Publicado: (2020)

Formulation and Evaluation of Supramolecular Food-Grade Piperine HP β CD and TPGS Complex: Dissolution, Physicochemical Characterization, Molecular Docking, In Vitro Antioxidant Activity, and Antimicrobial Assessment
por: Imam, Syed Sarim, et al.
Publicado: (2020)

Development and Evaluations of Transdermally Delivered Luteolin Loaded Cationic Nanoemulsion: In Vitro and Ex Vivo Evaluations
por: Altamimi, Mohammad A., et al.
Publicado: (2021)

Propyl 4-hydroxybenzoate
por: Zhou, Yiwen, et al.
Publicado: (2010)

Formulation of Piperine-Loaded Nanoemulsion: In Vitro Characterization, Ex Vivo Evaluation, and Cell Viability Assessment
por: Alshehri, Sultan, et al.
Publicado: (2023)

Novel Approach for Transdermal Delivery of Rifampicin to Induce Synergistic Antimycobacterial Effects Against Cutaneous and Systemic Tuberculosis Using a Cationic Nanoemulsion Gel
por: Hussain, Afzal, et al.
Publicado: (2020)

Synergistic Effect of Acetazolamide-(2-hydroxy)propyl β-Cyclodextrin in Timolol Liposomes for Decreasing and Prolonging Intraocular Pressure Levels
por: Arroyo-García, Carmen M., et al.
Publicado: (2021)

Cyclodextrin Multicomponent Complexes: Pharmaceutical Applications
por: Aiassa, Virginia, et al.
Publicado: (2021)

Feasibility of Using Gluconolactone, Trehalose and Hydroxy-Propyl Gamma Cyclodextrin to Enhance Bendroflumethiazide Dissolution Using Lyophilisation and Physical Mixing Techniques
por: Saleh, Ashraf, et al.
Publicado: (2018)

Complexation with Random Methyl-β-Cyclodextrin and (2-Hydroxypropyl)-β-Cyclodextrin Promotes Chrysin Effect and Potential for Liver Fibrosis Therapy
por: Ignat, Simona-Rebeca, et al.
Publicado: (2020)

Mechanistic Insights into Luteolin-Loaded Elastic Liposomes for Transdermal Delivery: HSPiP Predictive Parameters and Instrument-Based Evidence
por: Altamimi, Mohammad A., et al.
Publicado: (2022)

Toxicological interaction between tobacco smoke toxicants cadmium and nicotine: An in-vitro investigation
por: Qamar, Wajhul, et al.
Publicado: (2021)

Enhanced Solubility and Stability of Aripiprazole in Binary and Ternary Inclusion Complexes Using Hydroxy Propyl Beta Cyclodextrin (HPβCD) and L-Arginine
por: Awais, Sophia, et al.
Publicado: (2023)

Enhanced Dissolution of Luteolin by Solid Dispersion Prepared by Different Methods: Physicochemical Characterization and Antioxidant Activity
por: Alshehri, Sultan, et al.
Publicado: (2020)

Optimized Green Nanoemulsions to Remove Pharmaceutical Enoxacin from Contaminated Bulk Aqueous Solution
por: Hussain, Afzal, et al.
Publicado: (2023)

Comparative Interaction Studies of Quercetin with 2-Hydroxyl-propyl-β-cyclodextrin and 2,6-Methylated-β-cyclodextrin
por: Vakali, Vasiliki, et al.
Publicado: (2022)

Optimization of Drug Permeation from 8% Ciclopirox Cyclodextrin/Poloxamer-Soluble Polypseudorotaxane-Based Nail Lacquers
por: Cutrín-Gómez, Elena, et al.
Publicado: (2020)

Improving the Solubilization and Bioavailability of Arbidol Hydrochloride by the Preparation of Binary and Ternary β-Cyclodextrin Complexes with Poloxamer 188
por: Anwer, Md. Khalid, et al.
Publicado: (2021)

Interaction of Chrysin and Its Main Conjugated Metabolites Chrysin-7-Sulfate and Chrysin-7-Glucuronide with Serum Albumin
por: Mohos, Violetta, et al.
Publicado: (2018)

Green Nanoemulsion Water/Ethanol/Transcutol/LabM-Based Treatment of Pharmaceutical Antibiotic Erythromycin-Contaminated Aqueous Bulk Solution
por: Hussain, Afzal, et al.
Publicado: (2022)

Effect of Penetration Enhancers on Drug Nail Permeability from Cyclodextrin/Poloxamer-Soluble Polypseudorotaxane-Based Nail Lacquers
por: Cutrín-Gómez, Elena, et al.
Publicado: (2018)

Crystal structure of 5-hydroxy-5-propylbarbituric acid
por: Gelbrich, Thomas, et al.
Publicado: (2015)

Effect of Roflumilast in airways disorders via dual inhibition of phosphodiesterase and Ca(2+)-channel
por: Imam, Faisal, et al.
Publicado: (2020)

Evaluation of the bioavailability of hydrocortisone when prepared as solid dispersion
por: Altamimi, Mohammad A., et al.
Publicado: (2019)

Formulation and evaluation of butenafine loaded PLGA-nanoparticulate laden chitosan nano gel
por: Alshehri, Sultan, et al.
Publicado: (2021)

Rosinidin Attenuates Lipopolysaccharide-Induced Memory Impairment in Rats: Possible Mechanisms of Action Include Antioxidant and Anti-Inflammatory Effects
por: Alshehri, Sultan, et al.
Publicado: (2021)

Effect on Nail Structure and Transungual Permeability of the Ethanol and Poloxamer Ratio from Cyclodextrin-Soluble Polypseudorotaxanes Based Nail Lacquer
por: Cutrín-Gómez, Elena, et al.
Publicado: (2018)

Cigarette waste: Assessment of hazard to the environment and health in Riyadh city
por: Qamar, Wajhul, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_f12u5l8j73bffsoss9tgdm6lem