ACTR5 controls CDKN2A and tumor progression in an INO80-independent manner

Epigenetic dysregulation of cell cycle is a hallmark of tumorigenesis in multiple cancers, including hepatocellular carcinoma (HCC). Nonetheless, the epigenetic mechanisms underlying the aberrant cell cycle signaling and therapeutic response remain unclear. Here, we used an epigenetics-focused CRISP...

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Detalles Bibliográficos
Autores principales: Xu, Xiaobao, Chan, Anthony K. N., Li, Mingli, Liu, Qiao, Mattson, Nicole, Pangeni Pokharel, Sheela, Chang, Wen-Han, Yuan, Yate-Ching, Wang, Jinhui, Moore, Roger E., Pirrotte, Patrick, Wu, Jun, Su, Rui, Müschen, Markus, Rosen, Steven T., Chen, Jianjun, Yang, Lu, Chen, Chun-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788768/
https://www.ncbi.nlm.nih.gov/pubmed/36563143
http://dx.doi.org/10.1126/sciadv.adc8911

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