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Regulation of eIF4E guides a unique translational program to control erythroid maturation

Translation control is essential in balancing hematopoietic precursors and differentiation; however, the mechanisms underlying this program are poorly understood. We found that the activity of the major cap-binding protein eIF4E is unexpectedly regulated in a dynamic manner throughout erythropoiesis...

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Detalles Bibliográficos
Autores principales:	Forester, Craig M., Oses-Prieto, Juan A., Phillips, Nancy J., Miglani, Sohit, Pang, Xiaming, Byeon, Gun Woo, DeMarco, Rachel, Burlingame, Al, Barna, Maria, Ruggero, Davide
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788769/ https://www.ncbi.nlm.nih.gov/pubmed/36563140 http://dx.doi.org/10.1126/sciadv.add3942

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