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Cryo-EM structure of the human adenosine A(2B) receptor–G(s) signaling complex

The human adenosine A(2B) receptor (A(2B)R) is a class A G protein–coupled receptor that is involved in several major physiological and pathological processes throughout the body. A(2B)R recognizes its ligands adenosine and NECA with relatively low affinity, but the detailed mechanism for its ligand...

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Detalles Bibliográficos
Autores principales:	Chen, Ying, Zhang, Jinyi, Weng, Yuan, Xu, Yueming, Lu, Weiqiang, Liu, Wei, Liu, Mingyao, Hua, Tian, Song, Gaojie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788782/ https://www.ncbi.nlm.nih.gov/pubmed/36563137 http://dx.doi.org/10.1126/sciadv.add3709

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