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Admission Blood Glucose Level as a Predictor of Outcome in Intensive Care Patients: A Cross-Sectional Study

Introduction: In the Intensive care unit (ICU), hyperglycemia is often observed; commonly associated with pre-existing diabetes or pre-diabetes or in nondiabetic patients. This study aimed to assess the role of admission blood sugar levels with outcomes in ICU patients. Methods: A total of 100 patie...

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Autores principales: Subramanian, Kalaivani, Radha, Devarajan, Narayanan, Namitha, Natarajaboopathi, Ravishankar, Reddy, Kotha Sugunakar, Shanagonda, Divya, Sakthivadivel, Varatharajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788787/
https://www.ncbi.nlm.nih.gov/pubmed/36578843
http://dx.doi.org/10.7759/cureus.32801
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author Subramanian, Kalaivani
Radha, Devarajan
Narayanan, Namitha
Natarajaboopathi, Ravishankar
Reddy, Kotha Sugunakar
Shanagonda, Divya
Sakthivadivel, Varatharajan
author_facet Subramanian, Kalaivani
Radha, Devarajan
Narayanan, Namitha
Natarajaboopathi, Ravishankar
Reddy, Kotha Sugunakar
Shanagonda, Divya
Sakthivadivel, Varatharajan
author_sort Subramanian, Kalaivani
collection PubMed
description Introduction: In the Intensive care unit (ICU), hyperglycemia is often observed; commonly associated with pre-existing diabetes or pre-diabetes or in nondiabetic patients. This study aimed to assess the role of admission blood sugar levels with outcomes in ICU patients. Methods: A total of 100 patients above 18 years of age were included in the study. A detailed history regarding the patient’s age, sex, and any chronic illness were taken. Heart rate, systolic blood pressure, and Glasgow coma scale (GCS) scores were recorded. Admission blood glucose level, blood urea, total leucocyte count, and serum electrolytes were measured; and the outcome was noted. Results: The number of diabetics was significantly higher (65.5%) in the random blood sugar (RBS) ≥180 group. Hyponatremia was significantly associated with hyperglycemia. Patients with hyperglycemia had serum bicarbonate <18. A significantly greater number of patients with hyperglycemia had GCS scores of <8, and required mechanical ventilation. The duration of ICU stay and non-survivors were significantly higher in the hyperglycemia group. Random blood sugar at admission as a factor to assess outcome showed a sensitivity of 68.4 and specificity of 59.3 with a cut-off value of 197. Conclusion: Admission of random blood sugar was significantly associated with poor outcomes. More stringent surveillance as well as routine blood glucose checks at the time of hospital admission should be emphasized.
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spelling pubmed-97887872022-12-27 Admission Blood Glucose Level as a Predictor of Outcome in Intensive Care Patients: A Cross-Sectional Study Subramanian, Kalaivani Radha, Devarajan Narayanan, Namitha Natarajaboopathi, Ravishankar Reddy, Kotha Sugunakar Shanagonda, Divya Sakthivadivel, Varatharajan Cureus Emergency Medicine Introduction: In the Intensive care unit (ICU), hyperglycemia is often observed; commonly associated with pre-existing diabetes or pre-diabetes or in nondiabetic patients. This study aimed to assess the role of admission blood sugar levels with outcomes in ICU patients. Methods: A total of 100 patients above 18 years of age were included in the study. A detailed history regarding the patient’s age, sex, and any chronic illness were taken. Heart rate, systolic blood pressure, and Glasgow coma scale (GCS) scores were recorded. Admission blood glucose level, blood urea, total leucocyte count, and serum electrolytes were measured; and the outcome was noted. Results: The number of diabetics was significantly higher (65.5%) in the random blood sugar (RBS) ≥180 group. Hyponatremia was significantly associated with hyperglycemia. Patients with hyperglycemia had serum bicarbonate <18. A significantly greater number of patients with hyperglycemia had GCS scores of <8, and required mechanical ventilation. The duration of ICU stay and non-survivors were significantly higher in the hyperglycemia group. Random blood sugar at admission as a factor to assess outcome showed a sensitivity of 68.4 and specificity of 59.3 with a cut-off value of 197. Conclusion: Admission of random blood sugar was significantly associated with poor outcomes. More stringent surveillance as well as routine blood glucose checks at the time of hospital admission should be emphasized. Cureus 2022-12-21 /pmc/articles/PMC9788787/ /pubmed/36578843 http://dx.doi.org/10.7759/cureus.32801 Text en Copyright © 2022, Subramanian et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Subramanian, Kalaivani
Radha, Devarajan
Narayanan, Namitha
Natarajaboopathi, Ravishankar
Reddy, Kotha Sugunakar
Shanagonda, Divya
Sakthivadivel, Varatharajan
Admission Blood Glucose Level as a Predictor of Outcome in Intensive Care Patients: A Cross-Sectional Study
title Admission Blood Glucose Level as a Predictor of Outcome in Intensive Care Patients: A Cross-Sectional Study
title_full Admission Blood Glucose Level as a Predictor of Outcome in Intensive Care Patients: A Cross-Sectional Study
title_fullStr Admission Blood Glucose Level as a Predictor of Outcome in Intensive Care Patients: A Cross-Sectional Study
title_full_unstemmed Admission Blood Glucose Level as a Predictor of Outcome in Intensive Care Patients: A Cross-Sectional Study
title_short Admission Blood Glucose Level as a Predictor of Outcome in Intensive Care Patients: A Cross-Sectional Study
title_sort admission blood glucose level as a predictor of outcome in intensive care patients: a cross-sectional study
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788787/
https://www.ncbi.nlm.nih.gov/pubmed/36578843
http://dx.doi.org/10.7759/cureus.32801
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