Fatal Acute Disseminated Encephalomyelitis Post-COVID-19 Vaccination: A Rare Case Report

Acute disseminated encephalomyelitis (ADEM) is a disease of the brain and spinal cord that is an immune-mediated inflammatory and demyelinating disorder, which is commonly preceded by an infection. Some reports have also shown the association of acute demyelination of the central nervous system (CNS...

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Autores principales: Nimkar, Shubham V, Yelne, Pallavi, Gaidhane, Shilpa A, Kumar, Sunil, Acharya, Sourya, Gemnani, Rinkle R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788800/
https://www.ncbi.nlm.nih.gov/pubmed/36579193
http://dx.doi.org/10.7759/cureus.31810
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author Nimkar, Shubham V
Yelne, Pallavi
Gaidhane, Shilpa A
Kumar, Sunil
Acharya, Sourya
Gemnani, Rinkle R
author_facet Nimkar, Shubham V
Yelne, Pallavi
Gaidhane, Shilpa A
Kumar, Sunil
Acharya, Sourya
Gemnani, Rinkle R
author_sort Nimkar, Shubham V
collection PubMed
description Acute disseminated encephalomyelitis (ADEM) is a disease of the brain and spinal cord that is an immune-mediated inflammatory and demyelinating disorder, which is commonly preceded by an infection. Some reports have also shown the association of acute demyelination of the central nervous system (CNS) with vaccination. Primarily, the involvement of the white matter of the cerebral hemispheres, brain stem, and spinal cord is observed. Such lesions should be considered as the differentials of ADEM. We would like to report a case of a 77-year-old female who was of post-COVID-19 vaccination status and presented to us with altered sensorium with imaging revealing acute demyelination.
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spelling pubmed-97888002022-12-27 Fatal Acute Disseminated Encephalomyelitis Post-COVID-19 Vaccination: A Rare Case Report Nimkar, Shubham V Yelne, Pallavi Gaidhane, Shilpa A Kumar, Sunil Acharya, Sourya Gemnani, Rinkle R Cureus Internal Medicine Acute disseminated encephalomyelitis (ADEM) is a disease of the brain and spinal cord that is an immune-mediated inflammatory and demyelinating disorder, which is commonly preceded by an infection. Some reports have also shown the association of acute demyelination of the central nervous system (CNS) with vaccination. Primarily, the involvement of the white matter of the cerebral hemispheres, brain stem, and spinal cord is observed. Such lesions should be considered as the differentials of ADEM. We would like to report a case of a 77-year-old female who was of post-COVID-19 vaccination status and presented to us with altered sensorium with imaging revealing acute demyelination. Cureus 2022-11-22 /pmc/articles/PMC9788800/ /pubmed/36579193 http://dx.doi.org/10.7759/cureus.31810 Text en Copyright © 2022, Nimkar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Nimkar, Shubham V
Yelne, Pallavi
Gaidhane, Shilpa A
Kumar, Sunil
Acharya, Sourya
Gemnani, Rinkle R
Fatal Acute Disseminated Encephalomyelitis Post-COVID-19 Vaccination: A Rare Case Report
title Fatal Acute Disseminated Encephalomyelitis Post-COVID-19 Vaccination: A Rare Case Report
title_full Fatal Acute Disseminated Encephalomyelitis Post-COVID-19 Vaccination: A Rare Case Report
title_fullStr Fatal Acute Disseminated Encephalomyelitis Post-COVID-19 Vaccination: A Rare Case Report
title_full_unstemmed Fatal Acute Disseminated Encephalomyelitis Post-COVID-19 Vaccination: A Rare Case Report
title_short Fatal Acute Disseminated Encephalomyelitis Post-COVID-19 Vaccination: A Rare Case Report
title_sort fatal acute disseminated encephalomyelitis post-covid-19 vaccination: a rare case report
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788800/
https://www.ncbi.nlm.nih.gov/pubmed/36579193
http://dx.doi.org/10.7759/cureus.31810
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