In rheumatoid arthritis patients, total IgA1 and IgA2 levels are elevated: implications for the mucosal origin hypothesis

OBJECTIVE: Mucosal initiated immune responses may be involved in the pathophysiology of RA. The most abundant immunoglobulin at mucosal surfaces is IgA, of which two subclasses exist: IgA1 and IgA2. IgA2 is mainly present at mucosal sites and has been ascribed pro-inflammatory properties. As IgA sub...

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Detalles Bibliográficos
Autores principales: Derksen, Veerle F A M, Allaart, Cornelia F, Van der Helm-Van Mil, Annette H M, Huizinga, Tom W J, Toes, René E M, van der Woude, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788813/
https://www.ncbi.nlm.nih.gov/pubmed/35416963
http://dx.doi.org/10.1093/rheumatology/keac237

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