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Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2

C-type lectin receptors (CLRs) elicit immune responses upon recognition of glycoconjugates present on pathogens and self-components. While Dectin-1 is the best-characterized CLR recognizing β-glucan on pathogens, the endogenous targets of Dectin-1 are not fully understood. Herein, we report that hum...

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Detalles Bibliográficos
Autores principales:	Haji, Shojiro, Ito, Taiki, Guenther, Carla, Nakano, Miyako, Shimizu, Takashi, Mori, Daiki, Chiba, Yasunori, Tanaka, Masato, Mishra, Sushil K, Willment, Janet A, Brown, Gordon D, Nagae, Masamichi, Yamasaki, Sho
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788829/ https://www.ncbi.nlm.nih.gov/pubmed/36479973 http://dx.doi.org/10.7554/eLife.83037

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