Exploring the inhibitory mechanisms of indazole compounds against SAH/MTAN-mediated quorum sensing utilizing QSAR and docking

The world is under the great threat of antimicrobial resistance (AMR) leading to premature deaths. Microorganisms can produce AMR via quorum sensing mechanisms utilizing S-adenosyl homocysteine/methylthioadenosine nucleosidase (SAH/MTAN) biosynthesis. But there is no specific drug developed to date...

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Detalles Bibliográficos
Autores principales: Nandi, Sisir, Kumar, Mohit, Kumari, Rashmi, Saxena, Aaruni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AboutScience 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788832/
https://www.ncbi.nlm.nih.gov/pubmed/36582781
http://dx.doi.org/10.33393/dti.2022.2512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788832/
https://www.ncbi.nlm.nih.gov/pubmed/36582781
http://dx.doi.org/10.33393/dti.2022.2512

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