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Attenuated humoral responses in HIV after SARS-CoV-2 vaccination linked to B cell defects and altered immune profiles
We assessed a cohort of people living with human immunodeficiency virus (PLWH) (n = 110) and HIV negative controls (n = 64) after 1, 2 or 3 SARS-CoV-2 vaccine doses. At all timepoints, PLWH had significantly lower neutralizing antibody (nAb) titers than HIV-negative controls. We also observed a dela...
Autores principales: | Touizer, Emma, Alrubayyi, Aljawharah, Ford, Rosemarie, Hussain, Noshin, Gerber, Pehuén Pereyra, Shum, Hiu-Long, Rees-Spear, Chloe, Muir, Luke, Gea-Mallorquí, Ester, Kopycinski, Jakub, Jankovic, Dylan, Jeffery-Smith, Anna, Pinder, Christopher L., Fox, Thomas A., Williams, Ian, Mullender, Claire, Maan, Irfaan, Waters, Laura, Johnson, Margaret, Madge, Sara, Youle, Michael, Barber, Tristan J., Burns, Fiona, Kinloch, Sabine, Rowland-Jones, Sarah, Gilson, Richard, Matheson, Nicholas J., Morris, Emma, Peppa, Dimitra, McCoy, Laura E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788849/ https://www.ncbi.nlm.nih.gov/pubmed/36590902 http://dx.doi.org/10.1016/j.isci.2022.105862 |
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