Open-Label, Randomized, Multicenter, Phase III Study Comparing Oral Paclitaxel Plus Encequidar Versus Intravenous Paclitaxel in Patients With Metastatic Breast Cancer

Intravenous paclitaxel (IVpac) is complicated by neuropathy and requires premedication to prevent hypersensitivity-type reactions. Paclitaxel is poorly absorbed orally; encequidar (E), a novel P-glycoprotein pump inhibitor, allows oral absorption. METHODS: A phase III open-label study comparing oral...

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Detalles Bibliográficos
Autores principales: Rugo, Hope S., Umanzor, Gerardo A., Barrios, Francisco J., Vasallo, Rosa H., Chivalan, Marco A., Bejarano, Suyapa, Ramírez, Julio R., Fein, Luis, Kowalyszyn, Ruben D., Kramer, E. Douglas, Wang, Hui, Kwan, Min-Fun R., Cutler, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2023
Materias:
ORIGINAL REPORTS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788977/
https://www.ncbi.nlm.nih.gov/pubmed/35858154
http://dx.doi.org/10.1200/JCO.21.02953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9788977/
https://www.ncbi.nlm.nih.gov/pubmed/35858154
http://dx.doi.org/10.1200/JCO.21.02953

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