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Surveillance of hemodialysis related infections: a prospective multicenter study

As in many countries, there is neither a surveillance system nor a study to reveal the hemodialysis (HD) related infection rates in Turkey. We aimed to investigate the infection rate among HD outpatients and implement CDC’s surveillance system. A multicenter prospective surveillance study is perform...

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Autores principales: Hasanoglu, Imran, Guner, Rahmet, Sahin, Suzan, Yılmaz Karadag, Fatma, Parmaksiz, Ergun, Atalay, H. Veli, Alısır Ecder, Sabahat, Arslan Gulen, Tugba, Atan Ucar, Zuhal, Karabay, Oguz, Sipahi, Savas, Kaya Kılıc, Esra, Duranay, Murat, Yapar, Derya, Dogan, İbrahim, Ersoz, Gulden, Turkmen, Gulcan, Kıykım, Ahmet Alper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789026/
https://www.ncbi.nlm.nih.gov/pubmed/36564392
http://dx.doi.org/10.1038/s41598-022-24820-3
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author Hasanoglu, Imran
Guner, Rahmet
Sahin, Suzan
Yılmaz Karadag, Fatma
Parmaksiz, Ergun
Atalay, H. Veli
Alısır Ecder, Sabahat
Arslan Gulen, Tugba
Atan Ucar, Zuhal
Karabay, Oguz
Sipahi, Savas
Kaya Kılıc, Esra
Duranay, Murat
Yapar, Derya
Dogan, İbrahim
Ersoz, Gulden
Turkmen, Gulcan
Kıykım, Ahmet Alper
author_facet Hasanoglu, Imran
Guner, Rahmet
Sahin, Suzan
Yılmaz Karadag, Fatma
Parmaksiz, Ergun
Atalay, H. Veli
Alısır Ecder, Sabahat
Arslan Gulen, Tugba
Atan Ucar, Zuhal
Karabay, Oguz
Sipahi, Savas
Kaya Kılıc, Esra
Duranay, Murat
Yapar, Derya
Dogan, İbrahim
Ersoz, Gulden
Turkmen, Gulcan
Kıykım, Ahmet Alper
author_sort Hasanoglu, Imran
collection PubMed
description As in many countries, there is neither a surveillance system nor a study to reveal the hemodialysis (HD) related infection rates in Turkey. We aimed to investigate the infection rate among HD outpatients and implement CDC’s surveillance system. A multicenter prospective surveillance study is performed to investigate the infection rate among HD patients. CDC National Healthcare Safety Network (NHSN) dialysis event (DE) protocol is adopted for definitions and reporting. During April 2016–April 2018, 9 centers reported data. A total of 199 DEs reported in 10,035 patient-months, and the overall DE rate was 1.98 per 100 patient-months. Risk of blood culture positivity is found to be 17.6 times higher when hemodialysis was through a tunneled catheter than through an arteriovenous fistula. DE rate was significantly lower in patients educated about the care of their vascular access site. Staphylococcus aureus was the most causative microorganism among mortal patients. Outcomes of DEs were hospitalization (73%), loss of vascular access (18.2%), and death (7.7%). This first surveillance study revealed the baseline status of HD related infections in Turkey and showed that CDC National Healthcare Safety Network (NHSN) DE surveillance system can be easily implemented even in a high workload dialysis unit and be adopted as a nationwide DE surveillance program.
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spelling pubmed-97890262022-12-25 Surveillance of hemodialysis related infections: a prospective multicenter study Hasanoglu, Imran Guner, Rahmet Sahin, Suzan Yılmaz Karadag, Fatma Parmaksiz, Ergun Atalay, H. Veli Alısır Ecder, Sabahat Arslan Gulen, Tugba Atan Ucar, Zuhal Karabay, Oguz Sipahi, Savas Kaya Kılıc, Esra Duranay, Murat Yapar, Derya Dogan, İbrahim Ersoz, Gulden Turkmen, Gulcan Kıykım, Ahmet Alper Sci Rep Article As in many countries, there is neither a surveillance system nor a study to reveal the hemodialysis (HD) related infection rates in Turkey. We aimed to investigate the infection rate among HD outpatients and implement CDC’s surveillance system. A multicenter prospective surveillance study is performed to investigate the infection rate among HD patients. CDC National Healthcare Safety Network (NHSN) dialysis event (DE) protocol is adopted for definitions and reporting. During April 2016–April 2018, 9 centers reported data. A total of 199 DEs reported in 10,035 patient-months, and the overall DE rate was 1.98 per 100 patient-months. Risk of blood culture positivity is found to be 17.6 times higher when hemodialysis was through a tunneled catheter than through an arteriovenous fistula. DE rate was significantly lower in patients educated about the care of their vascular access site. Staphylococcus aureus was the most causative microorganism among mortal patients. Outcomes of DEs were hospitalization (73%), loss of vascular access (18.2%), and death (7.7%). This first surveillance study revealed the baseline status of HD related infections in Turkey and showed that CDC National Healthcare Safety Network (NHSN) DE surveillance system can be easily implemented even in a high workload dialysis unit and be adopted as a nationwide DE surveillance program. Nature Publishing Group UK 2022-12-23 /pmc/articles/PMC9789026/ /pubmed/36564392 http://dx.doi.org/10.1038/s41598-022-24820-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Hasanoglu, Imran
Guner, Rahmet
Sahin, Suzan
Yılmaz Karadag, Fatma
Parmaksiz, Ergun
Atalay, H. Veli
Alısır Ecder, Sabahat
Arslan Gulen, Tugba
Atan Ucar, Zuhal
Karabay, Oguz
Sipahi, Savas
Kaya Kılıc, Esra
Duranay, Murat
Yapar, Derya
Dogan, İbrahim
Ersoz, Gulden
Turkmen, Gulcan
Kıykım, Ahmet Alper
Surveillance of hemodialysis related infections: a prospective multicenter study
title Surveillance of hemodialysis related infections: a prospective multicenter study
title_full Surveillance of hemodialysis related infections: a prospective multicenter study
title_fullStr Surveillance of hemodialysis related infections: a prospective multicenter study
title_full_unstemmed Surveillance of hemodialysis related infections: a prospective multicenter study
title_short Surveillance of hemodialysis related infections: a prospective multicenter study
title_sort surveillance of hemodialysis related infections: a prospective multicenter study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789026/
https://www.ncbi.nlm.nih.gov/pubmed/36564392
http://dx.doi.org/10.1038/s41598-022-24820-3
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