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Continuous cholinergic-dopaminergic updating in the nucleus accumbens underlies approaches to reward-predicting cues

The ability to learn Pavlovian associations from environmental cues predicting positive outcomes is critical for survival, motivating adaptive behaviours. This cued-motivated behaviour depends on the nucleus accumbens (NAc). NAc output activity mediated by spiny projecting neurons (SPNs) is regulate...

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Detalles Bibliográficos
Autores principales: Skirzewski, Miguel, Princz-Lebel, Oren, German-Castelan, Liliana, Crooks, Alycia M., Kim, Gerard Kyungwook, Tarnow, Sophie Henke, Reichelt, Amy, Memar, Sara, Palmer, Daniel, Li, Yulong, Jane Rylett, R., Saksida, Lisa M., Prado, Vania F., Prado, Marco A. M., Bussey, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789106/
https://www.ncbi.nlm.nih.gov/pubmed/36564387
http://dx.doi.org/10.1038/s41467-022-35601-x