Prolonged Dexamethasone Exposure Enhances Zebrafish Lateral-Line Regeneration But Disrupts Mitochondrial Homeostasis and Hair Cell Function

The synthetic glucocorticoid dexamethasone is commonly used to treat inner ear disorders. Previous work in larval zebrafish has shown that dexamethasone treatment enhances hair cell regeneration, yet dexamethasone has also been shown to inhibit regeneration of peripheral nerves after lesion. We ther...

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Detalles Bibliográficos
Autores principales: Saettele, Allison L., Wong, Hiu-tung C., Kindt, Katie S., Warchol, Mark E., Sheets, Lavinia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789251/
https://www.ncbi.nlm.nih.gov/pubmed/36261670
http://dx.doi.org/10.1007/s10162-022-00875-x

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