A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility

Chemical synapses between axons and dendrites mediate neuronal intercellular communication. Here, we describe a synapse between axons and primary cilia: the axo-ciliary synapse. Using enhanced focused ion beam-scanning electron microscopy on samples with optimally preserved ultrastructure, we discov...

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Detalles Bibliográficos
Autores principales: Sheu, Shu-Hsien, Upadhyayula, Srigokul, Dupuy, Vincent, Pang, Song, Deng, Fei, Wan, Jinxia, Walpita, Deepika, Pasolli, H. Amalia, Houser, Justin, Sanchez-Martinez, Silvia, Brauchi, Sebastian E., Banala, Sambashiva, Freeman, Melanie, Xu, C. Shan, Kirchhausen, Tom, Hess, Harald F., Lavis, Luke, Li, Yulong, Chaumont-Dubel, Séverine, Clapham, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789380/
https://www.ncbi.nlm.nih.gov/pubmed/36055200
http://dx.doi.org/10.1016/j.cell.2022.07.026

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