Cargando…

Pattern and predictors of medication use among adults in southwestern Nigeria: A community‐based cross‐sectional study

Population‐based drug utilization studies are scanty in Nigeria. The aim was to determine the pattern and predictors of medication use among adults in the communities of Southwestern Nigeria. A cross‐sectional study was conducted among adults selected by multi‐stage sampling from Oyo State communiti...

Descripción completa

Detalles Bibliográficos
Autores principales: Adedeji, Waheed Adeola, Dairo, Magbagbeola David, Nguku, Patrick Mboya, Oyemakinde, Akin, Fehintola, Fatai Adewale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789472/
https://www.ncbi.nlm.nih.gov/pubmed/36565158
http://dx.doi.org/10.1002/prp2.1017
_version_ 1784858962352406528
author Adedeji, Waheed Adeola
Dairo, Magbagbeola David
Nguku, Patrick Mboya
Oyemakinde, Akin
Fehintola, Fatai Adewale
author_facet Adedeji, Waheed Adeola
Dairo, Magbagbeola David
Nguku, Patrick Mboya
Oyemakinde, Akin
Fehintola, Fatai Adewale
author_sort Adedeji, Waheed Adeola
collection PubMed
description Population‐based drug utilization studies are scanty in Nigeria. The aim was to determine the pattern and predictors of medication use among adults in the communities of Southwestern Nigeria. A cross‐sectional study was conducted among adults selected by multi‐stage sampling from Oyo State communities. The questionnaires, adapted from the WHO Students' Drug Use Questionnaire and previous studies, were pretested and interviewer administered. The respondents' socio‐demographic characteristics, the pattern of medication use, prescribers, and sources of drug acquisition were obtained. Binary logistic regression was used to determine the predictor of medications used. Of the 999 respondents, 501 resided in rural communities while 498 dwelled in urban areas. The mean (±SD) age of the respondents was 38 ± 15 years. The median (range)% prevalence of medication use were as follows: lifetime use, 58.2 (17.7–81.0); current use, 31.2 (8.9–65.9); and past use, 20.3 (9.2–28.9). Medications were mainly obtained from patent medicine stores, median (range%), 71 (65–80). The commonly used drugs were paracetamol, 626 (67.6); nonsteroidal anti‐inflammatory drugs, 174 (18.8); artemether/lumefantrine, 422 (68.2); ampicillin/cloxacillin, 220 (48.6); and chlorpheniramine, 59 (39.9). Factors predictive of current medication use, adjusted odd ratio (95% confidence interval) were as follows: antimalarial [male, 0.7 (0.5, 0.9)]; antibacterial [male, 0.6 (0.4–0.9)]; analgesics [married, 1.5 (1.1–2.2); presence of health facilities, 0.5 (0.3–0.7); and shorter distance to health facility, 1.5 (1.1–2.1)]. Antimalarials, antibacterial, and analgesics were commonly used and inappropriately obtained by adults in Southwestern Nigeria. Factors predictive of current medication use were gender, marital status, the presence of health facilities, and distance to health facilities. There is a need for more extensive countrywide medication use studies and enlightenment programs to ensure the appropriate use of medications.
format Online
Article
Text
id pubmed-9789472
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-97894722022-12-28 Pattern and predictors of medication use among adults in southwestern Nigeria: A community‐based cross‐sectional study Adedeji, Waheed Adeola Dairo, Magbagbeola David Nguku, Patrick Mboya Oyemakinde, Akin Fehintola, Fatai Adewale Pharmacol Res Perspect Original Articles Population‐based drug utilization studies are scanty in Nigeria. The aim was to determine the pattern and predictors of medication use among adults in the communities of Southwestern Nigeria. A cross‐sectional study was conducted among adults selected by multi‐stage sampling from Oyo State communities. The questionnaires, adapted from the WHO Students' Drug Use Questionnaire and previous studies, were pretested and interviewer administered. The respondents' socio‐demographic characteristics, the pattern of medication use, prescribers, and sources of drug acquisition were obtained. Binary logistic regression was used to determine the predictor of medications used. Of the 999 respondents, 501 resided in rural communities while 498 dwelled in urban areas. The mean (±SD) age of the respondents was 38 ± 15 years. The median (range)% prevalence of medication use were as follows: lifetime use, 58.2 (17.7–81.0); current use, 31.2 (8.9–65.9); and past use, 20.3 (9.2–28.9). Medications were mainly obtained from patent medicine stores, median (range%), 71 (65–80). The commonly used drugs were paracetamol, 626 (67.6); nonsteroidal anti‐inflammatory drugs, 174 (18.8); artemether/lumefantrine, 422 (68.2); ampicillin/cloxacillin, 220 (48.6); and chlorpheniramine, 59 (39.9). Factors predictive of current medication use, adjusted odd ratio (95% confidence interval) were as follows: antimalarial [male, 0.7 (0.5, 0.9)]; antibacterial [male, 0.6 (0.4–0.9)]; analgesics [married, 1.5 (1.1–2.2); presence of health facilities, 0.5 (0.3–0.7); and shorter distance to health facility, 1.5 (1.1–2.1)]. Antimalarials, antibacterial, and analgesics were commonly used and inappropriately obtained by adults in Southwestern Nigeria. Factors predictive of current medication use were gender, marital status, the presence of health facilities, and distance to health facilities. There is a need for more extensive countrywide medication use studies and enlightenment programs to ensure the appropriate use of medications. John Wiley and Sons Inc. 2022-12-24 /pmc/articles/PMC9789472/ /pubmed/36565158 http://dx.doi.org/10.1002/prp2.1017 Text en © 2022 The Authors. Pharmacology Research & Perspectives published by British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Adedeji, Waheed Adeola
Dairo, Magbagbeola David
Nguku, Patrick Mboya
Oyemakinde, Akin
Fehintola, Fatai Adewale
Pattern and predictors of medication use among adults in southwestern Nigeria: A community‐based cross‐sectional study
title Pattern and predictors of medication use among adults in southwestern Nigeria: A community‐based cross‐sectional study
title_full Pattern and predictors of medication use among adults in southwestern Nigeria: A community‐based cross‐sectional study
title_fullStr Pattern and predictors of medication use among adults in southwestern Nigeria: A community‐based cross‐sectional study
title_full_unstemmed Pattern and predictors of medication use among adults in southwestern Nigeria: A community‐based cross‐sectional study
title_short Pattern and predictors of medication use among adults in southwestern Nigeria: A community‐based cross‐sectional study
title_sort pattern and predictors of medication use among adults in southwestern nigeria: a community‐based cross‐sectional study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789472/
https://www.ncbi.nlm.nih.gov/pubmed/36565158
http://dx.doi.org/10.1002/prp2.1017
work_keys_str_mv AT adedejiwaheedadeola patternandpredictorsofmedicationuseamongadultsinsouthwesternnigeriaacommunitybasedcrosssectionalstudy
AT dairomagbagbeoladavid patternandpredictorsofmedicationuseamongadultsinsouthwesternnigeriaacommunitybasedcrosssectionalstudy
AT ngukupatrickmboya patternandpredictorsofmedicationuseamongadultsinsouthwesternnigeriaacommunitybasedcrosssectionalstudy
AT oyemakindeakin patternandpredictorsofmedicationuseamongadultsinsouthwesternnigeriaacommunitybasedcrosssectionalstudy
AT fehintolafataiadewale patternandpredictorsofmedicationuseamongadultsinsouthwesternnigeriaacommunitybasedcrosssectionalstudy