Methionine regulates self-renewal, pluripotency, and cell death of GIC through cholesterol—rRNA axis

BACKGROUND: Glioma-initiating cells (GICs) are the source of glioma cells that can self-renew, have pluripotency, and are treatment-resistant, so are the starting point for relapse and eventual death despite multimodality therapy. L-[methyl-(11)C] methionine PET has observed high accumulation at the...

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Detalles Bibliográficos
Autores principales: Yokogami, Kiyotaka, Kikuchi, Taisei, Watanabe, Takashi, Nakatake, Yasutaka, Yamashita, Shinji, Mizuguchi, Asako, Takeshima, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789638/
https://www.ncbi.nlm.nih.gov/pubmed/36564758
http://dx.doi.org/10.1186/s12885-022-10280-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789638/
https://www.ncbi.nlm.nih.gov/pubmed/36564758
http://dx.doi.org/10.1186/s12885-022-10280-5

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